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ea0029p787 | Endocrine tumours and neoplasia | ICEECE2012

Expression of a novel isoform of thyroid peroxidase (TPO) gene in breast cancer (BC)

Muller I. , Giani C. , Fiore E. , Belardi V. , Sabatini S. , Rosellini V. , Funel N. , Campani D. , Grennan-Jones F. , Zhang L. , Lewis M. , Bakhsh A. , Roncella M. , Ghilli M. , Pinchera A. , Vitti P. , Dayan C. , Ludgate M.

Introduction: BC patients have a high prevalence of anti-TPO-autoantibodies (TPOAb), which seem to be protective in BC patients. We hypothesized the presence of T-lymphocytes citotoxicity against a common antigen between thyroid and BC cells.Aim: To evaluate the possible expression of TPO gene in BC.Materials: Frozen tissue specimens: 8 BC, 5 peri-tumoral breast tissues (PT), 3 pancreatic adenocarcinoma (P), 2 kidney cancers (K) an...

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Endocrine Abstracts

Expression of a novel isoform of thyroid peroxidase (TPO) gene in breast cancer (BC)

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