Searchable abstracts of presentations at key conferences in endocrinology

ea0081p533 | Adrenal and Cardiovascular Endocrinology | ECE2022

Renin indicates the mineralocorticoid activity of fludrocortisone: a 6-year study in primary adrenal insufficiency

Ceccato Filippo , Torchio Marianna , Tizianel Irene , Barbot Mattia , Sabbadin Chiara , Betterle Corrado , Scaroni Carla

Context: Fludrocortisone (FC) is the mineralocorticoid (MC) replacement treatment for patients with primary adrenal insufficiency (PAI). Objective: To explore the dose of FC treatment and its relationship with glucocorticoid therapy, sodium, potassium, renin and clinical parameters. Design: Longitudinal study.Setting: Monocentric cohort.Patients: Data of 193 patients with PAI (130 autoi...

ea0063gp192 | Adrenal and Neuroendocrine - Clinical | ECE2019

Diagnostic accuracy of captopril challenge test and saline infusion test in patients at high risk for primary aldosteronism

Ceccato Filippo , Barbot Mattia , Sabbadin Chiara , Lolli Jacopo , Antonelli Giorgia , Plebani Mario , Boscaro Marco , Scaroni Carla

Background and aim: Aldosterone-to-Renin Ratio (ARR) is recommended as initial test to screen for Primary Aldosteronism (PA), especially in high-risk hypertensive population. Endocrine Society (ES) Guidelines recommend that patients with an increased ARR should undergo one or more confirmatory tests in order to confirm or exclude PA diagnosis. Captopril Challenge Test (CCT) and Saline Infusion Test (SIT) are commonly used in routine clinical practice. The aim of our study was ...

ea0056p56 | Adrenal cortex (to include Cushing's) | ECE2018

Improved salivary cortisol rhythm with dual-release hydrocortisone

Ceccato Filippo , Selmin Elisa , Sabbadin Chiara , Costa Miriam Dalla , Antonelli Giorgia , Plebani Mario , Barbot Mattia , Betterle Corrado , Boscaro Marco , Scaroni Carla

Introduction and aim: The purpose of replacement therapy in Adrenal Insufficiency (AI) is mimicking endogenous cortisol levels as closely as possible: dual release hydrocortisone (DR-HC) has been introduced to replicate the circadian cortisol rhythm. Multiple daily saliva collections could be used to assess the cortisol concentration during real-life: our aim was to study the salivary cortisol rhythm in AI.Materials and methods: We prospectively evaluate...

ea0073pep14.7 | Presented ePosters 14: COVID-19 | ECE2021

Psychological distress in patients with hypocortisolism during mass quarantine for Covid-19 epidemic in Italy

Simeoli Chiara , Barbot Mattia , Franco Marta , Martino Marianna , Morelli Valentina , Ferraù Francesco , Paragliola Rosa Maria , Hasenmajer Valeria , Guarnotta Valentina , Filpo Giuseppina De , Giordano Roberta , Dalmazi Guido Di , Sabbadin Chiara , Veresani Alessandro , Isidori Andrea M. , Mantovani Giovanna , Arnaldi Giorgio , Boschetti Mara , Scaroni Carla , Colao Annamaria , Iasevoli Felice , Pivonello Rosario

Beyond the huge impact on physical health, coronavirus disease-19 (COVID-19) epidemic represents a significant psychological stressor, causing effects on mental health. The psychological distress of the epidemic and consequent mass quarantine on patients with hypocortisolism, particularly frail and vulnerable to infections and stress, is unknown. The current multicentre, web-survey-based, case-control study evaluated the psychological impact of COVID-19 quarantine in a large c...