Searchable abstracts of presentations at key conferences in endocrinology

ea0041ep1007 | Thyroid (non-cancer) | ECE2016

Thyroid dyshormonogenesis: therapeutic data of a group of seventeen patients

Cheikhrouhou Nesrine , Mnif Mouna , Mnif Fatma , Salah Dhouha Ben , Abid Mohamed

Introduction: Thyroid dyshormonogenesis (TD) accounts for 15–20% of congenital hypothyroidism (CH). Levothyroxine is the treatment of choice with the immediate goal to raise the serum T4 as rapidly as possible. Surgical treatment is indicated in case of compressive or suspected goiter.Patients and methods: Seventeen patients with thyroid dyshormonogenesis belonging to 4 Tunisian families were included in a descriptive prospective study. They were fo...

ea0037ep251 | Calcium and Vitamin D metabolism | ECE2015

Low bone mass in Sheehan's syndrome: prevalence and management

Chihaoui Melika , Salah Dhouha Ben , Yazidi Meriem , Chaker Fatma , Ftouhi Bochra , Slimane Hedia

Introduction: Hypopituitarism is a known cause of bone mineral loss. Our study aimed to evaluate the frequency of osteopenia and osteoporosis in patients with Sheehan’s syndrome and to evaluate its management.Subjects and methods: It is a retrospective longitudinal study concerning 60 cases of Sheehan’s syndrome that have had a bone mineral density measurement. The parameters of osteodensitometry, the received treatment and the follow up data w...

ea0056p1088 | Thyroid (non-cancer) | ECE2018

Dysthyroidism and chromosomal aberrations

Ghorbel Dorra , Mnif Fatma , Chebbi Donia , Salah Dhouha Ben , Rekik Nabila , Abid Mohamed

Introduction: Dysthyroidism is not uncommon during chromosomal aberrations. The objective of this work is to study the characteristics of this association at the epidemiological and clinical levels.Methods: This is a retrospective study of 27 cases of patients with trisomy 21 chromosomal abnormalities (6 cases), klinefelter syndrome (4 cases) and Turner syndrome (17 cases) genetically confirmed, collected at endocrinology service at Sfax University Hospi...

ea0063p834 | Adrenal and Neuroendocrine Tumours 3 | ECE2019

Familial multiple endocrine neoplasia type 1 revealed by a maxillary swelling

Salah Dhouha Ben , Gargouri Imen , Mnif Fatma , Elleuch Mouna , Charfi Nadia , Mnif Mouna , Rekik Nabila , Abid Mohamed

Introduction: Multiple endocrine neoplasia type 1 (MEN1) is a rare autosomal dominant disorder caused by mutations in the MEN1 tumor suppressor gene and is characterized clinically by tumors in two or more endocrine glands, such as the pituitary gland, parathyroid glands or pancreatic islets. We describe an atypical presentation of familial hyperparathyroidism evoking the diagnosis of MEN1 in the first place.Observations: We report a three-member family....

ea0063p1097 | Pituitary and Neuroendocrinology 3 | ECE2019

Predictive factor of hypopituitarism in prolactinoma

Elleuch Mouna , Loukil Fatma , Mnif Fatma , Salah Dhouha Ben , Hadjkacem Faten , Mnif Mouna , Charfi Nedia , Rekik Nabila , Abid Mohamed

Intoduction: Pitiutary tumor is considered as the first etiology responsable of secondary hypopituitarism. Hypogonadotropic hypogonadism is the most commonly reported lesion.Meterials and methods: It is a retrospective study including 77 cases of prolactinoma. The data collection was done over 17 years, between 2000 and 2017.Results: Gonadotropic deficiency was confirmed in 48 patients (63.6%). A significant negative correlation wa...

ea0070aep742 | Pituitary and Neuroendocrinology | ECE2020

Visual impairment in patients with pituitary apoplexy

Gargouri Imen , Faten Hadjkacem , Wafa Belabed , Salah Dhouha Ben , Mouna Mnif , Nadia Charfi , Nabila Rekik , Mohamed Abid

Introduction: Pituitary apoplexy (PA) is a rare incident defined by the occurrence of necrosis and/or haemorrhage of the pituitary gland. PA is a clinical syndrome characterized by the sudden onset of headache, vomiting, visual impairment and decreased consciousness in some cases. The objectives of our study are to describe its clinical features and characterize the visual impairments in a cohort of PA in the region of Sfax.Methods: It is a retrospective...

ea0063p844 | Adrenal and Neuroendocrine Tumours 3 | ECE2019

Association of neurofibromatosis type 1 and neuroendocrine tumor

Kacem Faten Hadj , Zargni Asma , Mnif Fatma , Rekik Fatma , Elleuch Mouna , Salah Dhouha Ben , Charfi Nedia , Mnif Mouna , Rekik Nabila , Abid Mohamed

Introduction: Pheochromocytoma occurs in 0.1–5.7% of patients with Neurofibromatosis type 1(NF1). We report two cases of adrenal pheochromocytoma in patients with NF1.Observation: A 46 year-old male was admitted to our department for further examinations of an adrenal mass. The CT-scan showed two well-defined right adrenal masses measuring each 128×87×86 mm and 60×52×37 mm with central necrosis and calcifications in the biggest o...

ea0063p1053 | Pituitary and Neuroendocrinology 3 | ECE2019

Prolactinoma and elderly subject: which caracteristics?

Elleuch Mouna , Loukil Fatma , Mnif Fatma , Safi Wajdi , Zargni Asma , Salah Dhouha Ben , Hadjkacem Faten , Mnif Mouna , Rekik Nabila , Charfi Nedia , Abid Mohamed

Introduction: Prolactinoma is the most common secretory pituitary adenomas. It has clinical and biological characteristics that depend on age, gender and tumor size. Prolactinoma of the old subject is a rare clinical form that was not sufficiently treated in the literature.Materiels and methods: It is a retrospective study including 77 cases of prolactinoma among which 3 cases aged over than 65 years. The collection of data was made between 2000 and 2017...

ea0063p1056 | Pituitary and Neuroendocrinology 3 | ECE2019

Pituitary stalk abnormalities: etiology aspects about 28 cases

Mnif Fatma , Safi Wajdi , Kacem Faten Hadj , Elarbi Kawthar , Khanfir Raoudha , Salah Dhouha Ben , Elleuch Mouna , Charfi Nadia , Rekik Nabila , Feki Mouna Mnif , Abid Mohamed

Introduction: The pituitary stalk is the target of various congenital or acquired pathologies. In this context we report a cohort of 28 patients with pathology of the pituitary stalk to analyze their clinical, hormonal and radiological characteristics.Results: The average age of our patients was 28 years with extremes ranging from (15 to 64); Male dominance was noted in 60% of cases. The reason for consultation was either a staturo delay or a pubertal de...

ea0063p1100 | Pituitary and Neuroendocrinology 3 | ECE2019

Outcome of prolactinoma during pregnancy

Elleuch Mouna , Loukil Fatma , Salah Dhouha Ben , Sahnoun Randa , Charfi Nedia , Mnif Fatma , Hadjkacem Faten , Mnif Mouna , Rekik Nabila , Abid Mohamed

Introduction: Infertility is a classic consequence of prolactinoma in women. The treatment of hyperprolactinemia allows the restoration of ovulatory cycles and therefore of fertility in 80–90% of cases.Methods and materials: The study is a retrospective cohort study done over 17 years from 2000 to 2017. It includes 77 cases of prolactinomas among which 12 women had one or more pregnancies after the diagnosis of prolactinoma.Re...