Searchable abstracts of presentations at key conferences in endocrinology

Endocrine Abstracts

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ea0046p6 | (1) | UKINETS2016

Whole-exome next generation sequencing of sporadic adrenocortical carcinomas - evidence for a proposed adenoma-carcinoma carcinogenesis sequence

Walls Gerard , Salatino Silvia , Wright Benjamin , Mihai Radu

Limited survival of patients with adrenocortical carcinoma (ACC) makes it imperative to understand the genetic basis of disease and support development of new therapies.Between 2010–2015, tissues from nine adrenalectomy patients (5M:4F, age 30–68 years) were snap frozen in liquid nitrogen and DNA extracted. Adjacent normal adrenal tissue (n=3) excised at adrenalectomy was collected as matched ‘normal’ controls. Whole-exome se...

Published by BioScientifica

Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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