Searchable abstracts of presentations at key conferences in endocrinology

ea0090ep138 | Calcium and Bone | ECE2023

Clinical characteristics of sporadic and MEN1-associated primary hyperparathyroidism in young patients

Aboishava Lizaveta , Elfimova Alina , Gorbacheva Anna , Salimkhanov Rustam , Eremkina Anna , Karaseva Elena , Mokrysheva Natalia

Introduction: Primary hyperparathyroidism (PHPT) is commonly the most early manifestation of multiple endocrine neoplasia syndrome type 1 (MEN1), but it can also occur in young patients without any inherited disorders. The aim of our study was to compare the clinical characteristics of PHPT in young patients with MEN1 syndrome and with sporadic disease.Patients and Methods: The study included 72 patients with MEN-1 associated PHPT and 168 patients with s...

ea0090ep238 | Diabetes, Obesity, Metabolism and Nutrition | ECE2023

A simultaneous pancreas-kidney transplantation for type 1 diabetes mellitus after a long-term period of hemodialysis (Clinical case)

Yevloyeva Madina , Salimkhanov Rustam , Katamadze Nino , Severina Anastasia , Shamkhalova Minara , Trubitsyna Natalia , Moysyuk Yan

Introduction: Today simultaneous pancreas-kidney transplantation (SPKT) is an effective method of treatment for patients with type 1 diabetes mellitus (T1D) and terminal stage of diabetic nephropathy (DN) on renal replacement therapy by hemodialysis. It solves several problems: reduces the severity of intoxication syndrome, contributes to the achievement of euglycemia in most cases, that allows to delay progression of micro- and macrovascular diabetic complications. Case Descr...

ea0090ep140 | Calcium and Bone | ECE2023

Patient with Ia pseudohypoparathyroidism and the novel mutation in the GNAS gene

Gorbacheva Anna , Salimkhanov Rustam , Pogoda Tatyana , Bogdanov Viktor , Zakharova Victoriya , Eremkina Anna , Mirnaya Svetlana , Melnichenko Galina , Mokrysheva Natalia

Introduction: Pseudohypoparathyroidism (PHP) is an orphan disease caused by a mutation in the GNAS gene encoding the α-subunit of G-protein. PHP is characterized by multihormonal resistance. A correlation between the genotype and phenotype of patients with GNAS mutations hasn’t yet been described.Clinical Case: Patient T., 19 years old male, admitted to our Centre with general weakness and overweight. Hypocalcemia, hyperphosph...