Searchable abstracts of presentations at key conferences in endocrinology

ea0056p224 | Calcium & Vitamin D metabolism | ECE2018

Clinical manifestation of Hypoparathyroidism in a monocentric cohort: our experience

Repaci Andrea , Altieri Paola , Dianori Francesco , Salituro Nicola , Vandi Giulia , Pagotto Uberto

Introduction: Hypoparathyroidism (HP) is characterized by low serum calcium and increased phosphate levels associated with inappropriately low serum PTH levels. Clinical manifestations of HP are tingling, muscle cramps, seizures, nephrocalcinosis, kidney stone, kidney failure, depression and anxiety.Objective: Quantify the chronic symptoms and complications of HP in our monocentric cohort.Material and methods: We conducted a retros...

ea0049ep1381 | Thyroid (non-cancer) | ECE2017

BRAFV600E status and Stimulated Thyroglobulin at ablation time increase prognostic value of American Thyroid Association (ATA) classification systems for persistent disease in Differentiated Thyroid Carcinoma (DTC)

Repaci Andrea , Vicennati Valentina , Paccapelo Alexandro , Salituro Nicola , Cavicchi Ottavio , Monari Fabio , Tallini Giovanni , Gruppioni Elisa , Altimari Annalisa , Fiorentino Michelangelo , Pagotto Uberto

Background: Stimulated Thyroglobulin levels measured at the time of remnant ablation (Htg-A) and BRAFV600E mutation were shown to have prognostic value in predicting persistent disease in DTC. The aim of this study was to evaluate the prognostic role of Htg-A combined with BRAFV600E status in association with revised American Thyroid Association (ATA) risk stratification.Patients and methods: 620 patients treated for a DTC were included in this study wit...

ea0070oc2.3 | Bone and Calcium | ECE2020

Prediction algorithm for persistent primary hyperparathyroidism after parathyroidectomy

Repaci Andrea , Vicennati Valentina , Salituro Nicola , Vandi Giulia , Zavatta Guido , Altieri Paola , Di Dalmazi Guido , Gambineri Alessandra , Pelusi Carla , Burgio Luca , Piccin Ottavio , Cavicchi Ottavio , Pagotto Uberto

Background: Primary hyperparathyroidism (PHPT) is characterized by an excessive secretion of the parathyroid hormone (PTH) with normal or high calcium levels. The gold standard therapy involves minimally invasive parathyroidectomy with intraoperative PTH (ioPTH) monitoring. Different criteria have been identified when predicting cure rates using ioPTH values.Objective: To evaluate the percent ioPTH drop (ΔioPTH), the post-excision ioPTH, the first p...

ea0070aep885 | Thyroid | ECE2020

Clinical severity score (CSS) and graves’ recurrent events after therapy (GREAT) score could predict radioiodine efficacy for treatment of Graves’ disease relapse

Repaci Andrea , Beleffi Michelle , Salituro Nicola , Colapinto Alessandra , Vicennati Valentina , Pelusi Carla , Altieri Paola , Gambineri Alessandra , Di Dalmazi Guido , Pagotto Uberto

Background: Antithyroid drugs (ATDs) are the first line treatment for Graves’ disease in Europe and Asia. However, their long term-efficacy is doubtful, with a high disease relapse rate after discontinuation. Radioiodine and surgery can be used as a second line therapy as definitive approaches after ATDs failure. In recent years, the GREAT and the CSS scores have been suggested to assess the risk of relapse at the time of disease onset, but no data are available about th...