Endocrine Abstracts

Introduction: Occult carcinoma of the thyroid is defined as a microcancer less than 1 cm in size, clinically undetectable. Discovered accidentally during routine radiological examination, cervical surgery of a benign thyroid tumor, varies from 0.01% to 35.6%. Mostly it is papillary type. Occult cancers revealed by bone metastasis have rarely been reported. We report two patient observations presenting bone localizations of occult thyroid carcinoma.Observ...

Polycystic ovary syndrome is the most common endocrine disorder of reproductive women. This syndrome is often associated with cardiovascular risk.Objective: Our objective was to assess the prevalence of cardiovascular factor in len PCOS women.Materials and methods: Sixty-eight lean PCOS were prospectively evaluated for glucose intolerance, dyslipidémie and high blood pressure from 2004 to 2007.Results: I...

Introduction: Autoimmune thyroid diseases are frequent and very polymorphic pathologies. The same person can successively present with different manifestations. Graves’ disease and Hashimoto’s thyroiditis seem to be able to coexist. The name "Hashitoxicosis" has been suggested in this case, characterized by the sequential association, whatever the order, of hyper- and hypothyroidism. We report in this work, the case of a patient treated for autoimmune hypothy...

Introduction : In the spectrum of endocrine emergencies, thyroid storm is one of the most critical complications. Recognition and appropriate management of life-threatening thyrotoxicosis is vital to prevent the high morbidity and mortality that may accompany this disorder. The incidence of thyroid storm has been noted to be less than 10% of patients hospitalized for thyrotoxicosis; however, the mortality rate secondary to thyroid storm ranges from 20 to 30%. We report in this...

Introduction: Thyroid carcinoma accounts for 1% of all thyroid tumours. Bone metastasis occurs in 10 to 40%, with skullmetastasis accounting for 2.5 to 5.8% of bone metastases. The largest series of skull metastasis from thyroid carcinoma described a frequency of only 2.5% among 473 patients. The majority of skull metastasis from thyroid cancers is of the follicular subtype. She can occur at any age, the youngest patient was just 18 years old but most patients are between 60 a...

The commonest site of metastasis from papillary carcinoma is regional lymph nodes. Distant metastases are rare, most presenting synchronously. Brain metastases in papillary carcinoma are rare, reported with a frequency of 0.1–5% and cavernous sinus metastasis is extremely rare.Case report: A 62-year-old woman presented with a history of non-secretory pituitary macroadenoma present with symptoms of hypopituitarism. MRI of the brain revealed a 4.5&#21...

Introduction: Hashimoto’s thyroiditis (HT) and Graves’ disease (GD) are two auto-immune diseases. They have different phenotypes and are generally believed to share a number of common etiological factors but the mechanisms leading to their dichotomy are unknown. An unusual outcome of HT is the conversion to GD.A mechanism that might be hypothesized to account for the change from HT to GD is the alteration in the biological activity of TSH recep...

Introduction: Cushing syndrome is a rare etiology of hirsutism and oligomenorrhea.Objective: Screening for Cushing’s syndrome (CS) in patients with hirsutism and oligomenorrhea.Patients and methods: A prospective study was performed from 2004 to 2012. 210 patients were admitted with the complain of hirsutism and oligomenorrhea. In order to establish the diagnosis and exclude the CS, all of them were evaluated with overnight de...

Introduction: Cushing’s syndrome is rare but severe because of his association with multiple complications and particularly increased cardiovascular factors. This complications determine a mortality rate four times higher than in general population.Objects: The aim of our study was to evalated the prevalence of cardiovascular factors in Cushing’ syndrome.Subjects and methods: Twenty-five patients with Cushing’ syndro...

Introduction: In the spectrum of endocrine emergencies, thyroid storm is one of the most critical complications. Recognition and appropriate management of life-threatening thyrotoxicosis is vital to prevent the high morbidity and mortality that may accompany this disorder. The incidence of thyroid storm has been noted to be less than 10% of patients hospitalized for thyrotoxicosis; however, the mortality rate secondary to thyroid storm ranges from 20 to 30%. We report in this ...