Endocrine Abstracts

Introduction: Pheochromocytoma is an endocrine tumor developed in the chromaffin cells of the adrenal medulla and excessively secreting catecholamines in varying amounts and types. It represents a rare tumor, often benign, but serious considering its mainly cardiovascular complications. The purpose of our study is to specify the revelation methods of pheochromocytomas in our population.Patients and methods: Our study has included 23 cases of pheochromocy...

Introduction: Malignant pheochromocytomas present a real challenge for practitioners. This entity of tumors is rare, with complex characterization, and heterogenocity in their evolution and prognosis. Given the rarity of this tumor group, there is no consensus on the therapeutic management. The management must be in a multidisciplinary framework. Through this illustrative case, we propose a literature review of this rare entity with discussion of the different therapeutic opti...

Introducing: Primary hyperparathyroidism (HPT1) is a frequent endocrinopathy. Diagnosed incidentally or in front of a urinary or bone symptomatology, we report a case of primary hyperparathyroidism in the mode of revelation makes the originality “a paralyzing sciatica”.Observation: The patient was 44 years old and was undergoing neurosurgery for chronic low back pain that was resistant to etiological treatment. In view of the persistent and hyp...

Introduction: The HAIR-AN syndrome, which consists of hyperandrogenism (HA), insulin resistance (IR) and acanthosis nigricans (AN), is an underdiagnosed endocrinopathy.Observation: We report the case of Miss A.M., 24 years old, admitted for exploration of hyperandrogenism. Anamnesis: the patient reported polyuropolydipsic syndrome and the notion of weight gain without eating disorders, making a total of 28 kg in 6 months. This period is also marked by th...

Introduction: Kallmann syndrome (KS) is a rare disorder. It is now designated as olfactogenital dysplasia with an association between agenesis of the olfactory bulbs and hypogonadism. The association of KS with a pituitary microadenoma has not been well described in the literature.Case report: It’s a 16-year-old and 6 months, admitted for evaluation of a micropenis, he has as ATCDs an orchidopexy performed at the age of 3 years, infertility in the m...

Systemic lupus erythematosus is a serious autoimmune disease characterised by the production of antinuclear antibodies directed particularly against native DNA. Its presence increases the susceptibility to develop other autoimmune diseases including autoimmune dysthyroidism. We present the case of a patient who presented with profound hypothyroidism as part of the work-up for lupus nephropathy. Female patient, 40 years old, reports physical asthenia for 2 months. On clinical e...

Introduction: -Thyroid disorders can predate or develop during pregnancy. -The effects on the fetus vary depending on the disease and the drugs used for treatment. But usually, untreated or undertreated hyperthyroidism can lead to harmful complications.Case report: It’s a 26-year-old patient with a history of goiter since childhood, history of goiter in the mother; grandmother and maternal aunt. the patient is 18 weeks pregnant, the pregnancy is unp...

Introduction: Pheochromocytoma is a rare tumor of chromaffin cells localized in the adrenal gland. It is responsible of secretion of catecholamines in a supra physiologic amount, leading to hypertension. Some patients may present with hypotension despite having high circulating levels of catecholamines. The challenge is to stabilize blood pressure by medication in cases with fluctuation of blood pressure.Case presentation: 49-year-old woman suffered from...

Introduction: Ganglioneuroma (GN) is a benign, well-differentiated nerve tumor composed of mature sympathetic ganglion cells and nerve fibers, and most commonly located in the posterior mediastinum and retroperitoneum. GN’s are rarely found in the adrenal gland. This tumor is usually asymptomatic and, in the majority of cases, detected incidentally. The diagnostic confirmation is histologic. We report a case of adrenal GN revealed by an adrenal incidentaloma.<p class=...

Introduction: Cushing’s syndrome (CS) is typically characterized by faciotronic obesity with signs of protein hypercatabolism, which may be iatrogenic or endogenous (adrenal or ATCH dependent). We report a case of CS of unusual presentation.Case Report: We report the case of a 45-year-old patient, referred for etiological assessment and management of an atypical cushing syndrome.– Symptomatology dates back to 2007, by the appearance of abdomina...