Endocrine Abstracts

We present a case of 40 years old lady who was referred to us with a thyroid nodule in her right lobe. She was well, but on specific questioning reported weight loss of about 3 kgs over the past month and some mild heat intolerance. The nodule was 2 cm in size and the patient was clinically euthyroid. Thyroid function tests demonstrated a suppressed serum TSH with a mildly elevated serum T3. A thyroid ultrasound scan was performed which demonstrated that the palpable nodule wa...

Introduction: Waterhouse Friedrichsen syndrome-Severe adrenal insufficiency is a rare but life-threatening condition secondary to bilateral adrenal haemorrhages. In many cases, it is caused by fulminant meningococcaemia, but there are numerous other aetiologies, it can also be caused by use of medications that promote blood clotting, reduce platelet count, primary antiphospholipid syndrome, renal vein thrombosis or steroid use and has been associated with splenectomy as well. ...

Selenium (Se) supplementation is recommended by the European Group (EUGOGO) for mildly active TED (200 mg/day for six-months) based on a seminal RCT which reported slowing of disease progression vs placebo. Treatment in Se deficient geographical areas may be particularly important. We recently reported Se deficiency in a cohort of 240 pregnant women in NI. The TEAMeD-NI group was set up in 2019 as part of the UK-wide quality improvement program to take a proactive approach to ...