Searchable abstracts of presentations at key conferences in endocrinology

ea0035p377 | Diabetes (epidemiology, pathophysiology) | ECE2014

Assessment of relaxin levels in pregnant women with gestational diabetes mellitus

Zaman Iftikhar , Swaminathan Ramasamyiyer , Brackenridge Anna , Sankaralingam Arun , McGowan Barbara

Introduction: Gestational diabetes mellitus (GDM) is an important co-morbidity of pregnancy, with insulin resistance a key contributor in its underlying pathology. Relaxin is a hormone considered crucial for mediating adaptations deemed vital for maintenance of pregnancy. Evidence has suggested that levels of plasma relaxin may be positively correlated with insulin sensitivity. This led us to hypothesize that relaxin may play a role in the pathogenesis of insulin resistance in...

ea0034p428 | Thyroid | SFEBES2014

The influence of thyrotoxicosis on circulating cortisol and response to Synacthen

Chowdhury Alex , Khanom Aziza , Agustsson Tomas , Sandhu Sunita , Sankaralingam Arun , Breen Louise , Powrie Jake , Thomas Stephen , McGowan Barbara

Background: It is recognised that there is ‘cross-talk’ between the thyroid and hypothalamo-pituitary–adrenal (HPA) axes. The few available studies suggest that cortisol levels may be low and cortisol metabolism altered in some patients with thyrotoxicosis.Aim: To compare HPA axis variables in the thyrotoxic state (TT) and euthyroid state (EU).Materials and methods: Short synacthen testing (250 μg tetracosactide...