Searchable abstracts of presentations at key conferences in endocrinology

ea0073aep504 | Pituitary and Neuroendocrinology | ECE2021

Acromegaly: Knowing the enemy in order to win

Porras Mariana Gomes , Alexa Benítez Valderrama , Paola Parra Ramírez , Rosa García Moreno , Rojas Patricia Martin , Gumersindo Fernández Vázquez , Beatriz Lecumberri Santamaría , Cristina Álvarez Escolá

IntroductionAcromegaly is an uncommon chronic disease with an insidious course. Due to the high morbimortality it causes, its early diagnosis and treatment are priority. The three therapeutic pillars are surgery, pharmacological treatment and radiotherapy, alone or in combination.ObjectivesTo clinically, biochemically and histologically characterize patients with acromegaly under follow-up in a tertiary hospi...

ea0073aep521 | Pituitary and Neuroendocrinology | ECE2021

Outcomes and complications of endoscopic pituitary surgery: A single-center study

Taibo Rocio Villar , Alicia Santamaría Nieto , Paula Andújar Plata , Antía Fernández Pombo , María Gemma Rodríguez Carnero , Ignacio Bernabeu Morón

ObjectivesTo present the results of our series of endoscopic surgery of PA, performed in a third level hospital by an experienced team.MethodsRetrospective review of PA undergoing endoscopic surgery between 2011 – 2018 in our institution. Clinical variables and radiological characteristics and outcomes were collected at diagnosis, before surgery and for an average of 4.8 years of postoperative follow-up....

ea0014p127 | (1) | ECE2007

Effectiveness of retinoic acid treatment for redifferentiation of thyroid cancer in relation to recovery of radioiodine uptake

Fernández Fernández Cristián A. , Puig-Domingo Manel , Lomeña Francisco , Estorch Montserrat , Bittini Angel L , Marazuela Mónica , Santamaría Javier , Martín Tomás , Martínez de Icaya Purificación , Moraga Immaculada , Cuesta María , Mejías Ana , Porta Manel , Mauricio Dídac , Halperin Irene

Retinoic acid (RA) treatment has been used in the last decade for redifferentiation of metastatic thyroid cancer that have lost radioiodine uptake (RIup) with heterogeneous results.Aim: To evaluate the improvement of RIup after a course of RA treatment.Method: Retrospective analysis of 29 patients with radioiodine negative metastatic disease (17 men /12 women; 22 papillary, 4 follicular and 3 oncocytic tumours). RA was given at a d...

ea0073aep478 | Pituitary and Neuroendocrinology | ECE2021

Uncured acromegaly, the dark side of the moon: a cross- sectional study

Porras Mariana Gomes , Alexa Benítez Valderrama , Álvaro Zamarrón Pérez , Carlos Pérez López , Isabel Esteban Rodríguez , Rosa García Moreno , Beatriz Lecumberri Santamaría , Cristina Álvarez Escolá

IntroductionAlthough surgical treatment of acromegaly is the treatment of choice in most patients, a wide therapeutic arsenal is available. Medical treatment can be indicated as primary treatment, complementary and even as pre-operative treatment.ObjectivesTo determine the prevalence of uncured acromegaly and the prevalence of controlled disease within this group. To clinically, biochemically and histological...

ea0070aep953 | Thyroid | ECE2020

Diagnostic patterns of relapsed differentiated thyroid cancer (DTC) and the efficacy of rescue therapies (ERUDIT Study)

Sambo Marcel , Navarro Elena , Aller Javier , Guadalix Sonsoles , Zafón Carlos , González Cristina , Santamaría Javier , González Marcelino , Puig Manel , Galofré Juan C. , Argüelles Iñaki , Vallejo Juan A. , Pubul Virginia , Santos Rita , Llanos Marta , Crespo Guillermo , Segura Ángel , Navarro Miguel , Gajate Pablo , Valdivia Javier , López Carlos , Castelo Beatriz , Villanueva María J. , Araujo Fábia , Orcajo Lorenzo , Rodríguez-Villanueva Julio

Introduction: Advanced differentiated thyroid carcinoma (aDTC) – herein defined as locally unresectable or metastatic disease – is one of the most common late-stage endocrine neoplasias. However, available data about its natural history is limited. ERUDIT is a multicenter, observational, retrospective study of patients diagnosed with aDTC in Spain and Portugal. The study describes its natural history from the initial diagnosis until the advanced stages of disease, ...

ea0073aep871 | Late Breaking | ECE2021

Relapsed Differentiated Thyroid Cancer, clinical presentation, treatment, and prognostic factors (ERUDIT Study)

Sambo Marcel , Elena Navarro González , Aller Pardo Javier , Guadalix Iglesias Sonsoles , Carles Zafón Llopis , Cintia González Blanco , Javier Santamaría Sandi , Marcelino Gómez Balaguer , Puig Domingo Manel , Juan C. Galofré Ferrater , Iñaki Argüelles Jiménez , Santos Rita , Marta Llanos Muñoz , Juan Antonio Vallejo Casas , Virginia Pubul Núñez , Crespo Herrero Guillermo , Ángel Segura Huerta , Miguel Navarro Martín , Gajate Borau Pablo , Valdivia Bautista Javier , Beatriz Castelo Fernández , Carlos López López , María J. Villanueva Silva , Orcajo Lorenzo , Julio Rodríguez-Villanueva García

Advanced differentiated thyroid carcinoma (aDTC), herein defined as locally unresectable and/or metastatic, is one of the most common late-stage endocrine neoplasias. However, available data about its natural history are limited. ERUDIT is a multicenter, observational, retrospective study of patients diagnosed with aDTC in Spain and Portugal. The study describes its natural history from the initial diagnosis until the advanced stages, focusing on specific characteristics of th...