Searchable abstracts of presentations at key conferences in endocrinology

ea0049oc5.4 | Cardiovascular Endocrinology | ECE2017

Food history characterization of Portuguese centenarians, nutritional biomarkers and cardiovascular risk: case control study

da Silva Alda Pereira , Chaves Catarina , Matos Andreia , Gil Angela , Santos Carolina , Valente Ana , Bicho Manuel , Clara Joao Gorjao

Introduction: Eating habits may contribute to longevity. Consumption of red meat, source of saturated fatty acids and cholesterol may be associated with increased risks of diabetes, cardiovascular disease (CVD), and mortality risk.Methods: We studied 521 subjects, both genders, 253 centenarians (CENT) (100.26±1.98 age) and 268 controls (67.51±3.25 age), both low (LCR) and high cardiovascular risk (HCR), calculated based on QRISK®2-2016. An...

ea0056p473 | Diabetes complications | ECE2018

The effect of glutathione S-transferase M1 and T1 polymorphisms on ascorbic acid plasma levels in diabetic patients

Valente Ana , Bicho Manuel , Carolina Santos Ana , Matos Andreia , Duarte Rui , Raposo Joao F , Costa Helena S

Introduction: Type 2 diabetes mellitus have been associated with excessive production of reactive oxygen species. Glutathione S-transferase (GST) polymorphisms result in decreased or absent enzyme activity and altered oxidative stress. Meta-analyses have indicated that deletion of either GSTM1 or GSTT1 is associated with a significant increased risk of coronary heart disease. The aim of this study was to evaluated if ascorbic acid (AA) plasma levels differ by GST genotype in d...

ea0073aep876 | Late Breaking | ECE2021

Influence of bitter taste gene TAS2R38 on endocrinometabolic and anthropometric parameters in a sample with thyroid disease

Mendes Costa Marta , Carolina Santos Ana , Ferreira Joana , Mário Rui Mascarenhas , Bicho Manuel , Paula Barbosa Ana , Alda Pereira da Silva

Background and objectivesTAS2R38 is a bitter taste gene that can influence food consumption depending on its single nucleotide polymorphisms (SNPs) leading to aminoacid substitutions in the receptor protein P49A (proline/alanine), A262V (alanine/valine) e V296I (valine/isoleucine). Subjects with at least one PAV (proline-alanine-valine) copy are bitter tasters, while AVI homozygotes are non-tasters. Other variants have intermediate bitter tasting: AAV&#6...