Endocrine Abstracts

A 23-year-old woman was referred with light periods and subfertility with a raised prolactin (1175 miu/l). Remaining pituitary function tests were normal. As she was now pregnant, investigations were postponed until post-pregnancy. Post-partum prolactin was 1823 miu/l and MRI pituitary demonstrated a 13.5 mm pituitary macroadenoma. Cabergoline was commenced but stopped due to a further pregnancy. At 22 weeks gestation she experienced left visual field loss. MRI showed...

A 29 year old woman, 21 weeks pregnant with no previous medical history was admitted with 5 days blurred vision in the left eye and headaches, worse in the morning and lying flat. Three weeks previously she had been treated with antibiotics for a group A strep infection. An urgent MRI suggested pituitary apoplexy with left optic chiasm nerve compression. IV hydrocortisone 100 mg TDS was commenced reduced to 20 mg TDS. Investigations showed TSH 0.2 mu/l, FT4 10.4 pmol/l, FT3 2....

Case History: A thirty year old female presented to hospital after a first seizure. She had no significant past medical history. She had a one week history of recurrent frontal headaches and had noticed irregular periods. There were no clinical features of acromegaly. CT and MRI brain imaging showed a 5 cm mass arising from the pituitary fossa, extending into the suprasellar cistern and anterior cranial fossa. There was evidence of mass effect on the optic nerves and optic chi...