Searchable abstracts of presentations at key conferences in endocrinology

ea0032p905 | Pituitary – Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2013

The effects of cabergoline treatment on cardiac valves in patients with prolactinoma

Sarac Fulden , Sarac Sefa , Tutuncuoglu Pelin

Introduction: Dopamine agonists have been reported to increase the risk of cardiac valve regurgitation in valve disease risks for 3 years treatment with cabergoline in patients with prolactinma. The aim of the study was to evaluate the frequency of cardiac valve diseases and regurgitation in patients with prolactinoma at the end of 3 years.Subjects and method: Thirty-one patients with prolactinoma who had received cabergoline following 3 years were enrol...

ea0037ep319 | Diabetes (pathiophysiology &amp; epitemiology) | ECE2015

Insulin receptor substrate 1 and 2 genes polymorphisms are associated with metabolic syndrome but not cardiovascular risk factors in patients with metabolic syndrome

Sarac Fulden , Sarac Sefa , Savas Sumru , Akcicek Fehmi

Objective: The aim of our study was to investigate the relationships between insulin receptor substrat-1 (IRS-1) and insulin receptor substrat-2 (IRS-2) gene polymorphisms and cardiovascular factors such as blood pressures, BMI, LDL- cholesterol, triglyceride, HOMA-IR, homocysteine, hsCRP and fibrinogen levels in patients with metabolic syndrome (MetS).Subjects and methods: The study population included 100 patients with MetS and 30 patients without MetS...

ea0056ep30 | Calcium and Bone | ECE2018

Evaluation of causes of high parathyroid hormone levels in elderly

Tutuncuoglu Pelin , Sarac Fulden

Primary hyperparathyroidism (PHPT) predominantly affects the elderly, with a peak incidence between ages 55 and 70. Parathyroid adenoma is the principal cause, representing 80–85% of all cases. The aim of the study to determine the frequency of parathyroid adenoma in elderly with high parathyroid hormone levels.Subjects and methods: We performed a retrospective analysis of 31 (30 female, 1 male) elderly wih high parathyroid hormone levels. The demog...

ea0032p506 | Endocrine disruptors | ECE2013

Endocrine functions in premenopausal and postmenopausal women

Sarac Fulden , Savas Sumru , Akcicek Fehmi

Introduction: The anabolic hormones, namely GH, testosterone and dehydroepiandrosterone, as well as the reproductive function of women, enter a period of progressive insufficiency which is characteristically designated as somatopause, andropause and adrenopause respectively. The aim of the study was to compare the endocrine functions between premenopausal and postmenopausal women.Subjects and methods: The study was included 40 premenopausal (mean age 34....

ea0032p1053 | Thyroid (non-cancer) | ECE2013

The characteristics of thyroid pathology in patients with parathyroid adenoma

Sarac Fulden , Savas Sumru , Akcicek Fehmi

Introduction: Thyroid and parathyroid pathology may coexist; classically, this is described in multiple endocrine neoplasia. Other nonsyndromic scenarios result in pathologies of these endocrine organs coexisting. The aim of the investigation the chracteristics of thyroid pathology in patients with parathyroid adenoma.Subjects and method: The study population included 42 (26 patients age <60 years vs 16 patients age ≥60 years) patients with par...

ea0056p9 | Adrenal cortex (to include Cushing's) | ECE2018

Evaluation of tumor size and hormonal status of elderly with adrenal incidentaloma

Sarac Fulden , Savas Sumru , Tutuncuoglu Pelin

Incidentalomas (AI) are clinically inapparent adrenal masses. Patients present hormone excess or mass effect, but part of them is clinically silent. They are discovered inadvertently in the course of diagnostic testing or treatment for other clinical conditions. The aim of the study was to investigate the clinical value of tumor size and hormonal status of elderly patients with adrenal incidentaloma (AI).Subjects and Methods: Forty-four elderly with AI w...

ea0056ep178 | Thyroid | ECE2018

A rare case of hurthle cell adenoma and parathyroid adenoma

Sarac Fulden , Savas Sumru , Tutuncuoglu Pelin

Introduction: Hurthle cell of adenoma (HCA)of thyroid gland is rare neoplasms of the thyroid. They have been found in association with various benign thyroid conditions like Hashimoto’s thyroiditis, hyperthyroidism, nodular goiter, and thyroid neoplasms; where they often represent oncocytic metaplasia. Oncocytic cells are also present in normal parathyroid tissue. Oncocytic parathyroid adenomas, predominantly (more than 70%) or exclusively composed of oncocytic cells are ...

ea0041ep1062 | Thyroid (non-cancer) | ECE2016

A nonspecific complaint such as diarrhea in elderly with hyperthyroidism: evaluation with a case

Sarac Sefa , Tutuncuoglu Pelın , Savas Sumru , Sarac Fulden

Introduction: Hyperthyroidism in the elderly can present with subtle nonspecific complaints. Patients with long-standing goiter can develop autonomous nodules resulting in toxic nodular goiter.Case report: An 86 year old women was referred from gastroenterologist for thyroid disease because of low TSH. She had diarrhea with five to eight bowel movements a day for six months. She denied palpitations, heat intolerance or muscle weakness. She had been noted...

ea0037ep131 | Reproduction, endocrine disruptors and signalling | ECE2015

25-Hydroxyvitamin D status in elderly patients with Hashimoto's thyroiditis

Sarac Fulden , Savas Sumru , Tutuncuoglu Pelin , Akcicek Fehmi

Introduction: Low serum levels of 25-hydroxyvitamin D (25(OH)D3) lower than has been reported to be prevalent in several autoimmune diseases. The aims of the study were i) to evaluate the 25(OH)D3 levels in patients with Hashimato’s thyroiditis (HT) and ii) to investigate the relationships between 25(OH)D3, TSH, free T4, free T3, and anti-thyroid peroxidase (anti-TPO) levels in elderly patients with HT.Subjects and method: Stud...

ea0037ep321 | Diabetes (pathiophysiology &amp; epitemiology) | ECE2015

Vitamin B12 levels and relationship between B12 and fasting insulin levels elderly patients with metabolic syndrome

Sarac Fulden , Savas Sumru , Sarac Sefa , Akcicek Fehmi

Introduction: Biochemical and clinical vitamin B12 deficiency has been demonstrated to be highly prevalent among patients with diabetes mellitus. The aims of the study were 1. to compare the vitamin B12 (VB12) levels, and 2. to investigate the relationship between VB12, fasting insulin and HOMA-IR levels in elderly patients with metabolic syndrome (MetS).Subjects and method: Study population included 121 (mean age 64.3±14.1 years) (80 female, 41 mal...