Searchable abstracts of presentations at key conferences in endocrinology

ea0037ep208 | Reproduction, endocrine disruptors and signalling | ECE2015

An endocrine disrupting chemical, bisphenol A: could it be associated with sex differentiation in brain regarding to transsexuality?

Yurekli Banu Sarer , Kutbay Nilufer Ozdemir , Saygili Fusun

Transsexuality is characterised by a belief of having been born in a wrong body. Sexual differentiation of genitals take place in the first 2 months of pregnancy. Sexual differentiation of brain takes place in the second half of pregnancy. It is found that there is structural sex differences in the central nucleus of the bed nucleus of the stria terminalis (BSTc). Structural differences were found to be reversed in transsexual people. In humans main mechanism appears to involv...

ea0037ep1339 | Clinical Cases–Thyroid/Other | ECE2015

A case of Swyer syndrome with gonadoblastoma and dysgerminoma

Yurekli Banu Sarer , Kutbay Nilufer Ozdemir , Ozen Samim , Karaca Emin , Acar Kamuran , Saygili Fusun

Aim: The Swyer syndrome belongs to a group of pure gonadal dysgenesis. Karyotype is 46,XY. Aberrations of chromosome Y or SRY gene mutation is present in 15–30% of cases. These patients have high gonadotropin levels and are classified as having hypergonadotropic hypogonadism. The Swyer syndrome in the female requires close followup because of the high risk of neoplastic transformation in the dysgenetic gonads. Herein we report a case of Swyer syndrome with gonadoblastoma ...

ea0035p521 | Endocrine tumours and neoplasia | ECE2014

A case of insulinoma localized in pancreas tail that cannot be monitored with endosonography and abdominal MR but with contrast abdominal BT

Kutbay Nilufer Ozdemir , Ocek Levent , Nart Deniz , Erdogan Mehmet , Cetinkalp Sevki , Ozgen A Gokhan , Saygili Fusun

Introduction: Insulinoma is a rare neuroendocrine tumor. 90% of insulinoma is solitaire and benign, and 10% is malignant. Although seen at any age, it is most commonly noticed in 4th and 6th decades.Case: A 78-year-old man was referred to a neurology clinic upon a sudden faint, disability to remember and meaningless behavior, and diagnosed with epilepsy in 2008. In 2012, he had a hypoglycemia attack (blood glucose 30 mg/dl) and was referred to Ege Univer...

ea0035p895 | Pituitary Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2014

Six cases of FSH/LH positive pituitary adenomas

Kutbay Nilufer , Yurekli Banu Sarer , Erdogan Mehmet , Saygili Fusun , Ertan Yesim

Introduction: Immunocytochemistry methods have demonstrated that most of the ‘clinically non functional’ adenomas are actually gonadotrophin secreting adenomas or gonadotroph adenomas. Gonadotroph adenomas are discovered in patients presenting with visual field disorder. Pituitary imaging almost always demonastrates macroadenoma. Anterior pituitary insufficiency is much more frequent than gonad hyperstimulation. Herein, we present six cases of FSH and/or LH positive ...

ea0020p118 | Thyroid | ECE2009

Demographic, clinical, laboratory, ultrasonographic and cytological features of patients with Hashimoto’s thyroiditis: results of a university hospital of 769 patients in Turkey

Erdogan Mehmet , Erdem Nihat , Cetinkalp Sevki , Ozgen Gokhan , Saygili Fusun , Yilmaz Candeger , Tuzun Mehmet , Kabalak Taylan

Background: We investigated the demographic and clinical features of patients with Hashimoto’s thyroiditis who had been diagnosed and treated in Ege University, the main referral center in the Aegean region of Turkey.Methods: Medical records of patients who had been followed in the endocrinology clinic of Ege University were retrospectively evaluated. Patients who had been diagnosed as having any thyroid disorder were determined. Patients with Hashi...

ea0020p387 | Diabetes and Cardiovascular | ECE2009

Plasma thrombin-activatable fibrinolysis inhibitor (TAFI) antigen levels in diabetic foot ulcers

Erdogan Mehmet , Solmaz Soner , Canataroglu Abdullah , Kulaksizoglu Mustafa , Cetinkalp Sevki , Ozgen Gokhan , Saygili Fusun , Yilmaz Candeger

Objective: Diabetic foot ulcer is associated with increased morbidity and mortality. The most important factor related to the development of foot ulcer is peripheral neuropathy. Thrombin-activatable fibrinolysis inhibitor (TAFI) is associated with coagulation, fibrinolysis and inflammation. Plasma TAFI may participate in arterial thrombosis in cardiovascular diseases (CVD). TAFI may be involved in the mechanism of vascular endothelial damage in diabetic patients. The aim of th...

ea0056p847 | Pituitary - Clinical | ECE2018

The Secret of the Ophtalmopathy

Simsir Ilgin Yildirim , Soyaltin Utku Erdem , Yurekli Banu Sarer , Yilmaz Mumtaz , Saygili Fusun

Although the first line therapy for prolactinoma is medical. Visual field defect due to pituitary mass would lead to surgery. Herein, we share the post-operative follow-up of a macroprolactinoma case.Case: A 57-year-old male patient was operated on for a giant pituitary adenoma, which was compressing the optic chiasm. The postop prolactin (PL) value was found to be higher than 200 ng/ml and cabergoline treatment was initiated. Two months after the operat...

ea0056ep107 | Pituitary and Neuroendocrinology | ECE2018

Could it be recurrent immunoglobulin G4-associated inflammatory mass at the hypothalamic region?

Erdem Soyaltin Utku , Simsir Ilgin Yildirim , Yurekli Banu Sarer , Saygili Fusun

Case: Thirty seven years old patient whose complaint was head ache was seen in the out patient clinic for the follow up of her hormone replacement therapy. First time she was admitted to hospital with the complaint of confusion was in 2013. Her cranial MRI revelaed enlargement of optic chiasma with the possible diagnossis of optic chiasmatic glioma. Biopsy was taken out from this mass twice in July and November of 2013. In histological examinations, there were B and T lymphocy...

ea0041ep102 | Bone &amp; Osteoporosis | ECE2016

A rare cause of hypocalcaemia: pseudohypoparathyroidism

Alp Gulay , Kutbay Nilufer Ozdemir , Yurekli Banu Sarer , Karaca Emin , Erdogan Mehmet , Cetinkalp Sevki , Ozgen Gokhan , Ozkinay Ferda , Saygili Fusun

Introduction: Pseudohypoparathyroidism (PHP) is a rare disease characterized by end-organ resistance to parathyroid hormone, causing hypocalcemia with hyperphosphatemia and elevated parathormone (PTH) levels. A prevalence of 3.4/million has been reported. Here, we present a rare case with PHP.Case report: A 28-year-old male patient with spasms in hands and feet was evaluated in the outpatient department of neurology and was referred to endocrinology clin...

ea0037ep3 | Adrenal cortex | ECE2015

A case of polyglandular autoimmune syndrome type 1 with hypercalcaemia and hypotension

Kutbay Nilufer Ozdemir , Yurekli Banu Sarer , Yaman Miray , Erdogan Mehmet , Cetinkalp Sevki , Saygili Fusun , Darcan Sukran , Ozgen Gokhan

Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) is also known as autoimmune polyendocrine syndrome type 1 (APS-1). We present a case of autoimmune polyendocrine syndrome type 1 with hypercalcaemia of adrenal insufficiency during the calcium treatment because of hypoparathyroidism.Case: A 20-year-old female patient was diagnosed with APS-1 in 2004. She applied to ER with the complaints of nausea and vomiting. Her laboratory finding...