Searchable abstracts of presentations at key conferences in endocrinology

ea0086pl6 | Society for Endocrinology Transatlantic Medal Lecture | SFEBES2022

The impact of adipocytes and adipose tissue on systemic metabolism

Scherer Philipp E

A number of different cell types contribute to the cellular architecture of fat tissue. While the fat cell is making important functional contributions to the systemic metabolic well-being, several additional cell types contribute a supportive role to bestow maximal flexibility on the tissue with respect to many biosynthetic and catabolic processes. The adipocyte has morphed into a cell type whose complexity we only start to appreciate. We now understand that: 1) the contribut...

ea0013p147 | Diabetes, metabolism and cardiovascular | SFEBES2007

Adiponectin complexes in human cerebrospinal fluid: distinct complex distribution from serum

Kusminski Christine , Kos Katarina , Schraw Todd , O’Hare Joseph , Ahima Rexford , Scherer Philipp , Kumar Sudhesh , McTernan Philip

Aims/hypothesis: Adiponectin is an adipocyte-derived secretory factor that is highly specifically expressed in adipocytes. It exerts effects on energy homeostasis via peripheral and central mechanisms. However, it is not clear whether adiponectin is crossing the blood brain barrier in humans. In serum, adiponectin circulates in several different complexes, each of which has distinct functions. Here, we wanted to test whether adiponectin can be found in human cerebrospinal flui...