Searchable abstracts of presentations at key conferences in endocrinology

ea0016p700 | Thyroid | ECE2008

Cigarette smoking but not the TSHR germline polymorphism D727E is associated with toxic multinodular goitre (TMNG) and the thyroid volume

Jorn Jakob , Miehle Konstanze , Schmidt Claudia , Wicht Juliane , Paschke Ralf

Objective: There are contradictory results regarding the possible association of the TSHR polymorphism D727E with TMNG. Furthermore the influence of smoking on the thyroid volume has been reported by several authors. A possible association of smoking with thyroid nodules and particularly TMNG has not been investigated up to date.Methods: In this study, 88 patients with TMNG were included. Diagnosis was verified by ultrasonography, scinthiscan, and measur...