Searchable abstracts of presentations at key conferences in endocrinology

ea0048wf4 | Workshop F: Disorders of the parathyroid glands, calcium metabolism and bone | SFEEU2017

Primary hyperparathyroidism due to parathyroid carcinoma

Thurtell Craig , Schofield Christopher

A previously well 50-year-old female was admitted to the acute medical unit with a 4-month history of fatigue, anorexia, polyuria, polydipsia and arthralgia. She was found to be hypercalcaemic with a corrected calcium of 3.84 mmol/l and, unexpectedly, an extremely elevated parathyroid hormone reported at >200 pmol/l. Other results included an elevated alkaline phosphatase, hypophosphataemia and normal renal function. Treatment with intravenous 0.9% sodium chloride and pami...

ea0015p95 | Clinical practice/governance and case reports | SFEBES2008

Impact of NICE guidelines for adult growth hormone replacement on practice in Scotland

Philip Sam , Howat Isabel , Carson Maggie , Booth Anne , Patterson Catherine , Schofield Christopher , Patrick Alan , Leese Graham , Bevan John , Connell John

Aim: To assess whether adults in Scotland currently receiving growth hormone (GH) meet the NICE criteria for starting and continuing GH replacement.Methods: We surveyed all endocrinologists in Scotland and identified the main centres using GH replacement. A cross-sectional case note review was carried out of all patients commenced on GH.Results: About 208 patients (51% women; 24% professionals, 90% Caucasian) were identified, 69 of...

ea0031p149 | Neoplasia, cancer and late effects | SFEBES2013

Epigenetic modifiers reduce proliferation of human neuroendocrine tumour cell lines

Lines Kate E , Gaynor Katherine U , Stevenson Mark , Newey Paul J , Piret Sian E , Filippakopoulos Panagis , Muller Susanne , Grozinsky-Glasberg Simona , Grossman Ashley B , Knapp Stefan , Schofield Christopher , Bountra Chas , Thakker Rajesh V

Neuroendocrine tumours (NETs), occurring at multiple sites including the pancreas, gastrointestinal tract, lung, thymus and pituitary, usually present at an advanced metastatic stage, and are increasing in incidence and prevalence as awareness and diagnostic techniques have improved. Treatments for NETs including surgery, drugs (e.g. somatostatin analogues), chemotherapy, radiotherapy and radionuclide therapy, are often not effective and as such additional therapeutic agents a...