ea0089o9 | Other | NANETS2022
Lou Emil
, Gandhi Nishant
, Farrell Alex
, Xiu Joanne
, Seeber Andreas
, Shaalan Beg Muhammad
, Darabi Sourat
, J. Demeure Michael
, Abraham Jim
, Oberley Matthew
, Marshall John
, Soares Heloisa
Background: SSTR substypes are collectively expressed in the majority of NENs. However, SSTR subtype expression is not routinely assessed for clinical decision-making, including patients eligible for targeted radionucleotide therapy. Elucidating the landscape of SSTR subtypes in context of molecular profiles for low-grade (LG-) and high-grade NENs (HG-NENs) provides an opportunity to better tailor targeted therapy. Here, we leverage the ability of transcriptomics to predict NE...