Searchable abstracts of presentations at key conferences in endocrinology

ea0037ep103 | Steroids, development and paediatric endocrinology | ECE2015

Leptin and kisspeptin evaluation in childhood obesity

Leo Francesco , Mancini Antonio , Segni Chantal Di , Raimondo Sebastiano , Barini Angelina , Curro Diego , Rossodivita Aurora Natalia

Kisspeptin is a neuropeptide secreted in anteroventral-periventricular and arcuate hypothalamic nuclei involved pubertal onset and in other functions of adult life. Kisspeptin levels are sex dependent, so they are higher in prepubertal girls and in adult women compared to age-matched male. This sex-related pattern has been reported in adult obesity, but few data are reported in childhood obesity. In order to evaluate correlations between metabolic status and kisspeptin, we stu...

ea0035p923 | Pituitary Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2014

Relationship between growth hormone deficiency and oxidative stress in patients with heart failure: Preliminary data.

Mancini Antonio , Raimondo Sebastiano , Segni Chantal Di , Gadotti Giovanni , Leo Francesco , Ierardi Carolina , Silvestri Sonia , Orlando Patrick , Tiano Luca , Pontecorvi Alfredo

It is well known that heart failure is associated with oxidative stress (OS). Reactive oxygen species in fact influence sarcolemmal and mitochondrial ione channels, which are responsible for cardiomyocyte excitability and are important in myocardial remodeling after a myocardial infarction. The decrease of anabolic axes can have a role in the progression of the illness.In order to evaluate the relationship between growth hormone deficiency (GHD) and inde...