Searchable abstracts of presentations at key conferences in endocrinology

ea0037ep965 | Thyroid (non-cancer) | ECE2015

Hypothyroidism and platelet parameters evaluation: a preliminary study

Scavuzzo Francesco , Genna Maria Ludovica , Nastri Gianluca , Serino Domenico , Volpe Raffaele

According to the findings of recent epidemiological research, thyroid complaints are among the most frequent endocrine illnesses in Italy. Being positively correlated to MPV, the mean platelet volume, in subjects with hypothyroidism, it has been hypothesised in literature that TSH can have a probable prothrombotic effect. The mean platelet volume (MPV), PCT (plateletcrit), PDV (platelet distribution width) and P-LCR (platelet large scale ratio) indicate the dimensions of plate...

ea0014p323 | (1) | ECE2007

Thyroid abnormalities during treatment with PEGIFNα-2a and PEGIFNα-2b in patients affected by HCV-related chronic disease: &br;a prospective randomized study

Scavuzzo Francesco , Monda Guido Di , Serino Domenico , Tartaglione Maria Teresa , Lampasi Filippo , Ascione Antonio , Volpe Raffaele

Background: Correlation between therapy with interferons, thyroid autoimmunity and dysfunction is widely reported. Currently we used two different pegilated-interferons (α-2a, α-2b).Aim: Evaluate a probable different behaviour of two PEG-IFN responsible of thyroid abnormalities.Patients and methods: We observed 236 consecutive naïve-patients with HCV-related chronic-disease undergoing a treatment with antiviral thera...

ea0081p313 | Diabetes, Obesity, Metabolism and Nutrition | ECE2022

Obesity and obesity-related diseases as a new clinical features in 3q27.3 microdeletion syndrome involving adipoq gene: a case study

De Brasi Davide , Novizio Vincenzo , Barba Livia , Scarano Elisabetta , Serino Domenico , Novizio Roberto , Della Monica Matteo , Petillo Roberta , Scavuzzo Francesco

Introduction: Adipose tissue is recognized as an important endocrine organ, secreting many endocrine factors. Adiponectin is the most abundant peptide released into circulation, encoded by ADIPOQ gene localized in chromosome 3q27.3. Adiponectin decreases intracellular ceramide, implicated in insulin resistance, inflammation and atherosclerosis. It stimulates fatty acid oxidation in skeletal muscle and inhibits glucose production in the liver. Hypo-adiponectinemia plays a centr...