ea0056gp269 | Thyroid non cancer - Benign Thyroid disease/ treatment | ECE2018
Virili Camilla
, Bruno Giovanni
, Santaguida Maria Giulia
, Porowska Barbara
, Capriello Silvia
, De Vito Corrado
, Severi Carola
, Centanni Marco
Hypothyroid patients with gastric disorders require a higher dose of oral thyroxine (T4) to reach target serum TSH. In vitro evidence supports the notion that the variations of gastric pH may also interfere with T4 dissolution profile. The present study is aimed at confirming in vivo the supposed correlation between the gastric pH, directly measured during endoscopy, and the therapeutic dose of thyroxine using a controlled treatment schedule. A total of 61 tablet T4-t...