Searchable abstracts of presentations at key conferences in endocrinology

ea0026p356 | Steroid metabolism | ECE2011

Hormonal parameters and sex hormone receptor gene polymorphisms in males with autoimmune diseases

Doukas Charalampos , Saltiki Katerina , Terzidis Kostas , Mantzou Aimily , Sarika Lida , Cimponeriu Andriana , Sfikakis Petros , Alevizaki Maria

Introduction: Autoimmune disease (AD) is more common in women than in men. Sex hormones may play a role. Sex hormone receptors (SHR) are expressed in cells of the autoimmune system. We investigated the possible role of hormonal parameters and of common gene polymorphisms of the estrogen receptor alpha (ESR1), beta (ESR2) and androgen receptor (AR) in the presence of AD in men.Methods: In total 227 men were studied; 125 had at least o...