Searchable abstracts of presentations at key conferences in endocrinology

ea0034p98 | Clinical practice/governance and case reports | SFEBES2014

Outcomes following pituitary surgery: a single centre audit

Manolopoulos Konstantinos , Bates Andrew S , Shad Amjad , Rahim Assad

Introduction: Pituitary surgery is associated with post-operative complications including hypopituitarism and visual field defects. In order to ensure that our surgical outcomes were comparable with other centres, we audited the outcome of a cohort of patients referred for surgery at a single centre.Methods: A retrospective audit of 27 consecutive patients diagnosed with pituitary adenoma at Heartlands Hospital Birmingham, who underwent trans-sphenoidal ...

ea0077p97 | Neuroendocrinology and Pituitary | SFEBES2021

Management of Complicated Pit-1 staining Non-functioning Pituitary macroadenoma in Pregnancy

Machenahalli Pratibha , Thandani Puja , Shad Amjad , Sherlala Khalid , Giovos Georgios , Dhingra Vandana , Randeva Harpal

Background: Incidence of non-functioning pituitary macroadenoma (NFPMA) is very rare in pregnancy. We describe a case of complicated non-functioning pituitary macroadenoma presented during pregnancy. 26 year old female at 21 weeks gestation presented to emergency services with worsening headaches, nausea and vomiting for 2-3 months. This was associated with transient double vision and confusion since 2 days. She was admitted to emergency department 3 weeks ago with vomiting an...

ea0075p07 | Pituitary and neuroendocrinology | EYES2021

Pregnancy and diabetes insipidus – A management conundrum

Thadani Puja , Khan Uzma , Giovos Georgios , Smith Megan , Dhingra Vandana , Shad Amjad , Randeva Harpal , Machenahalli Pratibha

Background: Diabetes Insipidus (DI) is uncommon during pregnancy. It may predate pregnancy, be unmasked by pregnancy or arise de novo during pregnancy secondary to other pathology. We present a case of DI in pregnancy to highlight challenges in management.Case Report: A 27-year-old lady at 21 weeks’ gestation, presented to A&E with worsening headache and confusion for three to five months. She was hemodynamically stable, had bitemporal hemianopi...

ea0086p110 | Neuroendocrinology and Pituitary | SFEBES2022

Retrospective analysis of clinical, biochemical, radiological features of Craniopharyngioma

Pratibha Machenahalli C , Iqbal Asif , Shad Amjad , Smith Megan , Woods Leanne , Brown Ian , Randeva Harpal

Craniopharyngioma is a rare embryonic malformation of the Sellar/parasellar region. This harbors BRAF-V600E mutations. There are 2 Subtypes-Adamantinomatous and Papillary. Point prevalence of CP is around 2/100,000 with no variance by gender or race. CP has bimodal age distribution with peak incidence in the ages of 5-14 and 65-74 years. CP presents with following clinical features: Symptoms due to increased intracranial pressure-Nausea, headaches, visual impairments, hormone ...

ea0086p115 | Neuroendocrinology and Pituitary | SFEBES2022

Pituicytoma mimicking as a Non-functioning pituitary macroadenoma

Kumarathunga P.A.D.M. , Machenahalli Pratibha , Shad Amjad , Smith Megan , Thadani Puja , Wellala A.V.H. , Randewa Harpal

Background: Pituitary adenomas are the commonest Sellar neoplasm, there are number of other differential diagnosis based on histopathological features and immune histochemical characteristics. Pituicytomas are rare tumours of sellar and suprasellar region which originate from pituicytes which are specialised glial cells of neurohypophysis and infundibulum.Case report: A 63-year-old lady with a background history of bilateral cataract corrected with surge...

ea0077p99 | Neuroendocrinology and Pituitary | SFEBES2021

Retrospective audit of clinical, biochemical and radiological features of Pituitary apoplexy

Machenahalli Pratibha , Shad Amjad , Shrelala Khalid , Thandani Puja , Giovos Georgios , Khan Uzma , Page Tristan , Haris Faiza , Smith Megan , Randeva Harpal

Background: Pituitary apoplexy is one of the rare endocrine emergencies. Most series indicate that incidence is between 2-7% based on clinical, surgical and histopathological evidence.1-3 Usually presents with severe headaches that may be associated with nausea vomiting, ocular palsies, fever, photophobia. Predisposing factors are pre-existing pituitary conditions, hypertension, major surgery, anticoagulation therapy, pregnancy, radiotherapy. Appropriate endocrine, ...

ea0059p134 | Neuroendocrinology and pituitary | SFEBES2018

Prolactin as a surrogate marker of prolactinoma diagnosis in PCOS

Dimitriadis Georgios K , Kyritsi Eleni Magdalini , Angelousi Anna , Mehta Hiten , Shad Amjad , Mytilinaiou Maria , Kaltsas Gregory , Randeva Harpal S

Background: To identify a serum prolactin (PRL) cut-off value indicative of a PRL-producing adenoma in women with polycystic ovarian syndrome (PCOS) and hyperprolactinaemia and characterize such patients. Materials and methods: In the present retrospective case–control study, the medical records of 528 PCOS women were reviewed. Pituitary magnetic resonance imaging (MRI) was performed in PCOS patients with PRL levels ≥94.0 ng/ml and/or symptoms suspicious of a pituit...