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ea0030oc2.5 | Oral Communications 2 | BSPED2012

Abnormal neurological and developmental outcomes in children with persistent and spontaneously resolving congenital hyperinsulinism

Avatapalle Bindu , Shah Sajni , Pryce Megan , Nicholson Jacqueline , Rigby Lindsey , Caine Louise , Didi Mohammed , Ehtisham Sarah , Patel Leena , Skae Mars , Padidela Raja , Banerjee Indraneel , Clayton Peter

Introduction: Neuroglycopaenia is recognised with abnormal neurology and development (Ab Dev) in 2644% of children with persistent congenital hyperinsulinism (P-CHI). The prevalence of Ab Dev in spontaneously resolving CHI (R-CHI) is not known. We aimed to investigate Ab Dev in R-CHI and P-CHI children in a contemporary cohort.Methods: All children (n=67) were assessed for Ab Dev in the domains of speech, language, motor and vision, and cate...

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Abnormal neurological and developmental outcomes in children with persistent and spontaneously resolving congenital hyperinsulinism

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