Searchable abstracts of presentations at key conferences in endocrinology

ea0038p78 | Clinical practice/governance and case reports | SFEBES2015

Pituicytoma, not a ‘meningioma’: late recurrence in a rare pituitary tumour

Yadagiri Mahender , Shaw Simon , Saravanappa Natarajan , Ayuk John , Jose Biju

Pituicytomas are rare tumours, originating from modified glial cells called pituicytes. The lineage of these tumours remains a topic of debate. Approximately 65 cases have been reported in the literature to date, since being formally recognised in 2007. We report a case where the final diagnosis was made after second surgery for late recurrence.Case: A 54-year-old man presented with left sided visual disturbances in 1998 and underwent transcranial resect...

ea0086p113 | Neuroendocrinology and Pituitary | SFEBES2022

A Rare Case of Radiation-Induced Sarcoma in Acromegaly – Diagnostic challenges

Basavaraju Navya , Shaw Simon , Varadhan Laks , Ayuk John , Saravanappa Natarajan , Jose Biju

Introduction: Acromegaly is a rare, progressive disease characterised by excess growth hormone. The recommended treatment is surgery. Radiotherapy and somatostatin analogues are used as adjuncts. The risk of post-radiotherapy osteosarcoma is 0.01% to 0.03% among all irradiated patients. We report a case of radiation-induced osteosarcoma that developed 22 years after radiotherapy for acromegaly.Case report: In 1997, a 53-year-old gentleman with acromegaly...

ea0044p144 | Neuroendocrinology and pituitary | SFEBES2016

Conservatively managed non-functioning pituitary adenoma – clinical and radiological course

Ahmed Farooq , Hashmi Zafar , Jadun Changez , Saravanappa Natarjan , Shaw Simon , Ayuk John , Jose Biju

Introduction: Clinically non-functioning pituitary adenoma (NFPA) represents up to 30% of pituitary tumours. Management is dictated by their size or mass effect. The natural progression of NFPA attracts debate as the evidence-base is limited.Methods: Conservatively managed NFPA patients were included. A single radiologist reviewed all images to avoid bias.Results: Forty-six patients were identified, 21 female. Four presented acutel...

ea0044p147 | Neuroendocrinology and pituitary | SFEBES2016

Incidental pituitary adenoma: clinical and radiological features

Hashmi Zafar , Gill Gurmit , Jadun Changez , Shaw Simon , Saravanappa Natarajan , Ayuk John , Jose Biju

Introduction: Incidental pituitary adenoma (IPA) is found in 10–20% autopsy and radiological series. These are being increasingly detected as access to sensitive imaging modalities improves.Methods: Patients with incidental pituitary findings between 2012 and 2016 were identified from local database. Referral details, clinical features and radiological findings were analysed. A single radiologist reviewed all images to avoid bias.<p class="abste...

ea0038p334 | Pituitary | SFEBES2015

Clinically non-functioning pituitary macroadenomas: presenting features and outcomes: recent experience at a tertiary centre

Yadagiri Mahender , Vijay Arun , Pritchard Mark , Nayak Ananth , Shaw Simon , Saravanappa Natarajan , Ayuk John , Jose Biju

Introduction: Non-functioning pituitary macroadenoma (NFMA) can cause considerable morbidity due to pituitary dysfunction and pressure effects. We present recent experience in managing cases diagnosed with NFMA at a single tertiary centre between January 2009 and October 2013.Results: Of the 63 patients with NFMA, 28 (44%) were females. Age ranged from 22 to 91 (mean 63). Visual disturbance symptoms (35/63; 57%) were the commonest presentation. Headache ...

ea0034p141 | Clinical practice/governance and case reports | SFEBES2014

Granulomatosis with polyangiitis presenting as a pituitary lesion

Christou Louise , Katreddy Mahesh , Dutta Shouma , Kamath Sanjeet , Shaw Simon , Jose Biju

Granulomatosis with polyangiitis (GPA), previously known as Wegener’s granulomatosis, is a rare heterogeneous vasculitic disease characterised by necrotising granulomatous inflammation typically affecting lungs and kidneys. GPA affecting pituitary is rare and usually results in posterior pituitary involvement causing diabetes insipidus. We describe a case of GPA, presenting with pituitary involvement causing headaches and anterior pituitary hormone deficiencies.<p cla...