Searchable abstracts of presentations at key conferences in endocrinology

ea0036oc3.8 | Oral Communications 3 | BSPED2014

Trends in off-label prescription of GH: results from the National GH Audit

Saraff Vrinda , Shepherd Sheila , Shaw Nick

Introduction: National Institute of Health and Care Excellence (NICE) has provided guidance for the use of human recombinant GH in the treatment of growth failure in children. An ongoing National GH Audit was established in 2013 by BSPED to maintain a central database and gather information regarding trends in prescribing and facilitate future long-term follow up. This part of the audit looked at the trends of off label prescribing of GH.Method: Data wer...

ea0033oc2.8 | Oral Communications 2 | BSPED2013

Establishing a national audit of paediatric GH prescribing

Gault Emma-Jane , Shepherd Sheila , Shaw Nick

Introduction: GH therapy is prescribed to UK children for a variety of indications. However, no central record exists, making follow-up studies difficult.Aim: To establish an ongoing audit of UK children and adolescents newly-prescribed GH in order to i) monitor trends in prescribing practice and ii) facilitate future long-term follow-up.Patient population: UK children aged ≤16.0 years newly starting GH therapy.<p class="...

ea0045p67 | Pituitary and growth | BSPED2016

Trends in growth hormone prescription in the UK: Results from the 3 year National Growth Hormone Audit

Saraff Vrinda , Shepherd Sheila , Patel Leena , Shaw Nick

Introduction: The National Growth Hormone (GH) audit was initiated in 2013 with funding from BSPED, to establish the ongoing trends in GH prescriptions in the UK and facilitate future long term follow up studies through a central database. Here we have studied the trends in GH prescribing and the indications for treatment from 2013 to 2015.Method: We examined data collected on a quarterly basis from centres across the UK on subjects less than 16 years of...

ea0036oc3.2 | Oral Communications 3 | BSPED2014

Vertebral fracture assessment in a paediatric population using dual-energy X-ray absorptiometry

Kyriakou Andreas , Shepherd Sheila , Lucaccioni Laura , Shaikh M Guftar , Mason Avril , Ahmed S Faisal

Background: Vertebral Fractures (VF) are recognized as an important aspect of bone health in children and adolescents. The clinical utility of vertebral fracture assessment (VFA) using dual-energy X-ray absorptiometry (DXA) has not been evaluated in the paediatric population.Method: VFA was performed independently by two non-radiologist observers, in 165 patients (77M/88F) as part of their investigation for low bone mineral density. Lateral thoracolumbar...

ea0058oc7.3 | Oral Communications 7 | BSPED2018

The determinants of skeletal morbidity and fractures in children with type 1 diabetes

Chen Suet Ching , Shepherd Sheila , McMillan Martin , McNeilly Jane , McComb Christie , Foster John , Wong Sze Choong , Robertson Kenneth J , Ahmed S Faisal

Objective: The pathophysiology of the increased fracture risk in Type 1 Diabetes (T1D) remains unclear. Given that childhood and adolescence are important physiological periods for optimal bone development, we performed a multimodality assessment to determine the effects of T1D on bone health.Methods: Thirty two affected children at a median (range) age of 13.7 years (10.4, 16.7), were recruited for detailed assessment of bone health. Serum bone alkaline...