Searchable abstracts of presentations at key conferences in endocrinology

ea0036oc4.6 | Oral Communications 4 | BSPED2014

Evaluating dipeptidyl peptidase-4 expression in patients with diffuse and focal congenital hyperinsulinism.

Rahman Sofia A , Sherif Maha M A , Tahir Sophia , Hussain Khalid

Background: Congenital hyperinsulinism (CHI) is the commonest cause of persistent hypoglycaemia and is due to the unregulated secretion of insulin from the pancreatic beta-cells. The role of gut hormones and dipeptidyl peptidase-4 (DPP-4) is currently unknown in patients with CHI.Aims: To evaluate the expression pattern of DPP-4 in focal and diffuse CHI.Method: Using intra-operative formalin-fixed paraffin embedded (FFPE) pancreati...