Searchable abstracts of presentations at key conferences in endocrinology

ea0081ep949 | Thyroid | ECE2022

Subacute thyroiditis in patients after COVID-19 infections at the outpatient stage

Shyshko Volha , Malakhava Darya , Yurenia Alena

Introduction: SARS-COV-2 is a new infection with little known consequences. As data accumulated, it became known that the thyroid gland is also affected as a result of infection. During the reconvalescence period, some patients developed severe thyrotoxicosis, which did not have the classic clinical picture of subacute thyroiditis or autoimmune.Aim: To study the course of subacute thyroiditis in patients after infection with COVID-19.<p class="abstex...

ea0063p561 | Diabetes, Obesity and Metabolism 2 | ECE2019

Features of type 2 diabetes mellitus in the elderly (Minsk)

Bilodid Irina , Shyshko Volha , Shalobyta N.

The article is devoted to one of the most pressing medical problems – diabetes mellitus type 2.Objective: To study the peculiarities of the course of diabetes mellitus type 2 in persons over 65 years of age; to evaluate the effectiveness of different therapy regimens for the level of HbA1C.Material and methods: The retrospective study included 100 patients with type 2 diabetes (T2D). The age of the patients: 65 to 82 years. Th...

ea0050p188 | Clinical Biochemistry | SFEBES2017

The state of glutathione system in patients with type 2 diabetes

Shyshko Volha , Mokhort Tatjana , Tsapaeva Natalia , Buko Inna

Introduction: Glutathione system prevents oxidative stress development in erythrocites. When this system becomes depressed it predisposes a cell to apoptosis.Aim: To study glutathione system status in patients with diabetesMaterials and methods: Included patients were divided into four groups: group 1–41 almost healthy person (control group), group 2–41 patients with type 2 diabetes (T2D), group 3–40 patients with T2...

ea0050p188 | Clinical Biochemistry | SFEBES2017

The state of glutathione system in patients with type 2 diabetes

Shyshko Volha , Mokhort Tatjana , Tsapaeva Natalia , Buko Inna

Introduction: Glutathione system prevents oxidative stress development in erythrocites. When this system becomes depressed it predisposes a cell to apoptosis.Aim: To study glutathione system status in patients with diabetesMaterials and methods: Included patients were divided into four groups: group 1–41 almost healthy person (control group), group 2–41 patients with type 2 diabetes (T2D), group 3–40 patients with T2...

ea0063gp127 | Diabetes: Late Complications | ECE2019

Genetic polymorphisms in patients with type 2 diabetes mellitus and coronary heart disease

Shyshko Volha , Mokhort Tatjana , Tsataeva Natalia , Konstantinova Elena , Gonchar Alexander

It is known that presence of certain genetic polymorphism plays important role in development of chronic complications in patients with type 2 diabetes (T2D).Aim: To analyze distribution of VEGF G/C polymorphisms and PAI-1 4G/5G polymorphisms in patients with T2D and IHD.Materials and methods: The following groups of studies were formed: 1 – 24 almost healthy people; 2 – 28 patients with prediabetes; 3 – 37 patients ...

ea0049ep527 | Diabetes complications | ECE2017

Correlation of NGAL and thyroid function in patients with type 1 diabetes

Sazonava Alena , Mokhort Tatiana , Shyshko Volha , Mokhort Alena , Karlovich Natalia

Neutrophil gelatinase-associated lipocalin (NGAL) was shown to be highly useful in assessing kidney injury in patients with diabetic nephropathy. Taking into account recent data that dysthyroidism may have reversible effects on GFR the purpose of the study was to investigate potential relationship between serum NGAL levels, thyroid status and ultrasound thyroid characteristics in patients with type 1 diabetes (T1D) with CKD.Materials and methods: We recr...

ea0049ep527 (1) | Diabetes complications | ECE2017

Correlation of NGAL and thyroid function in patients with type 1 diabetes

Sazonava Alena , Mokhort Tatiana , Shyshko Volha , Mokhort Alena , Karlovich Natalia

Neutrophil gelatinase-associated lipocalin (NGAL) was shown to be highly useful in assessing kidney injury in patients with diabetic nephropathy. Taking into account recent data that dysthyroidism may have reversible effects on GFR the purpose of the study was to investigate potential relationship between serum NGAL levels, thyroid status and ultrasound thyroid characteristics in patients with type 1 diabetes (T1D) with CKD.Materials and methods: We recr...

ea0049ep663 | Obesity | ECE2017

Results of computer-assisted intravital microscopy in overweight and obesity

Shyshko Volha , Mokhort Tatjana , Konstantinova Elena , Tsapaeva Natalia

Rationale: Obesity, prediabetes and diabetes are strongly associated with microcirculation (MC) abnormalities. It is known that pathological changes in microvessels predispose to CHD, CKD and retinopathy. Also it is widely recognized that biochemical and immunological changes accompanied with obesity and overweight lead to MC damage.ObjectiveOf the study was to assess changes in MC in patients with overweight and obesity.<p cla...

ea0041ep454 | Diabetes (to include epidemiology, pathophysiology) | ECE2016

PAI-1 polymorphism in patients with diabetes

Shyshko Volha , Mokhort Tatjana , Gonchar Alexander , Konstantinova Elena , Tsapaeva Natalia

Background: Plasminogen activator inhibitor-1 (PAI-1) refers to group of is a serine protein inhibitors. It inhibits fibrinolysis and contributes to angiogenesis and atherogenesis processes. 4G/5G polymorphism was found to be associated with increased risk for cardiovascular diseases. It was of special interest to study PAI-1 polymorphism in patients with diabetes.Aim: Aim to study PAI-1 polymorphism in patients with type 2 diabetes (T2D) and concomitant...

ea0041ep514 | Diabetes complications | ECE2016

Assessment of neutrophil gelatinase-associated lipocalin in diabetic patients

Sazonava Alena , Mokhort Tatiana , Shyshko Volha , Mokhort Alena , Shishko Elena

Background: Diabetic nephropathy (DN) is a major cause of morbidity and mortality in type 1 diabetes (T1D) patients and associated with increased cardiovascular risk in type 2 diabetes (T2D) patients. Early detection of DN using neutrophil gelatinase-associated lipocalin (NGAL) assessment can help to reveal predisposed patients to its progression and to prevent progression of DN. Especially important it is in patients with normoalbuminuria.Aim: To determ...