ea0049ep807 | Nuclear receptors and Signal transduction | ECE2017
Cardoso Sarah
, Andrade Matheus
, Cunha Vinicius
, Silva Cristian
, Rodrigues Patricia
, Leao Mayra
, Fagg Christopher
, Guerra Eliete
, Neves Francisco
, Simeoni Luiz
, Silveira Damaris
, Lofrano-Porto Adriana
Introduction: Prostate cancer is a public health problem worldwide. The cure is unlikely and therapeutic alternatives are limited. The Brazilian biodiversity represents a huge source of potential discovery of new drugs derived from plants. We therefore aimed to conduct a biomonitoring chemical study of plant extracts from Pouteria sp. previously shown to be cytotoxic in androgen-sensitive (LNCaP) and androgen-resistant (PC3) human prostate cancer cell lines.<p cla...