Searchable abstracts of presentations at key conferences in endocrinology

ea0016p93 | Bone and calcium | ECE2008

Insulin sensitivity and lipid status before and after radical treatment of primary hyperparathyroidism

Kendereski Aleksandra , Micic Dragan , Cvijovic Goran , Zoric Svetlana , Sumarac-Dumanovic Mirjana , Pejkovic Danica , Simic Maja

It was previously shown that patients with primary hyperparathyroidism (PHPT) are insulin resistant. The aim of our study was to evaluate the effect of surgical treatment on insulin sensitivity and lipid levels in patients with PHPT. In 21 patients with PHPT (age: 56.24±8.69 years, BMI 25.2±3.81 kg/m2) lipid levels (TC, HDL, LDL, TG, Lp(a)) and insulin sensitivity were determinated before and 4 months after surgical treatment. Insulin sensitivity was evalu...

ea0016p568 | Obesity | ECE2008

Relationship between obesity, IL-17 and IL-23 and insulin resistance

Sumarac-Dumanovic Mirjana , Micic Dragan , Simic Maja , Stamenkovic-Pejkovic Danica , Stevanovic Darko , Jorga Jagoda , Cvijovic Goran , Zoric Svetlana , Trajkovic Vladimir

In most obese patients, obesity is associated with a low-grade inflammation of white adipose tissue resulting from chronic activation of the innate immune system and which can subsequently lead to insulin resistance, impaired glucose tolerance and even diabetes. It is still not clear role of acquired immune response in obesity and related comorbidites such as asthma, cancer or autoimmune diseases. The aim of our study was to compare level s of IL-17 and IL23 in sever obese wom...

ea0016p570 | Obesity | ECE2008

C-reactive protein and insulin sensitivity in severe obese women with and without metabolic syndrome

Simic Maja , Micic Dragan , Sumarac-Dumanovic Mirjana , Stamenkovic-Pejkovic Danica , Jorga Jagoda , Cvijovic Goran , Kendereski Aleksandra , Zoric Svetlana

It was postulated that different therapeutic approaches could influence the markers of inflammation in obesity but it is unknown whether overweight women with and without metabolic syndrome have the same degrees of inflammatory state. The aim of our study was to compare level of hs-CRP in obese women without other components of metabolic syndrome with hs-CRP in women with metabolic syndrome (according IDF criteria). Overweight body mass index-matched women without (OW)) (n<...

ea0016p561 | Obesity | ECE2008

The interrelationship between leptin, visfatin and CRP levels and insulin sensitivity assessed by euglycaemic clamp in obese women

Micic Dragan , Sumarac-Dumanovic Mirjana , Stamenkovic-Pejkovic Danica , Simic Maja , Cvijovic Goran , Zoric Svetlana , Kendereski Aleksandra , Stevanovic Darko , Jorga Jagoda , Trajkovic Vladimir

Visfatin is a newly discovered adipokine found in abundance in visceral fat. Leptin is well known marker of fat mass in the body but also one aspect of leptin is its action as a proinflammatory cytokine. Recent studies, both in vitro and in vivo, indicated that visfatin is also one of the inflammatory cytokines, although the relationship between visfatin and insulin resistance remains still unclear. The aim of our study was to assess the association between visfa...