ea0104p147 | Neuroendocrinology | SFEIES24
Fensome Grace
, Simmonds Livia
, Wood Stephen
, Hardy Rowan
, Khanim Farhat
, Shaheen Fozia
, Taylor Angela
, Reniers Renate
Background: The hormone cortisol is both induced by and is a biomarker of stress. However, its long-term measurement in blood and urine is limited by feasibility of collection. Hair is a novel matrix to measure long-term steroid levels. We developed a liquid chromatography-tandem mass spectrometry (LC/MS) method to assess hair cortisol in individuals at ultra-high risk (UHR) for psychosis as a biomarker of stress.Method: Hair samples from 10 UHR individu...