Searchable abstracts of presentations at key conferences in endocrinology

ea0104p147 | Neuroendocrinology | SFEIES24

Assessing biological stress markers in the hair of individuals at ultra-high risk for psychosis using a novel method of extraction

Fensome Grace , Simmonds Livia , Wood Stephen , Hardy Rowan , Khanim Farhat , Shaheen Fozia , Taylor Angela , Reniers Renate

Background: The hormone cortisol is both induced by and is a biomarker of stress. However, its long-term measurement in blood and urine is limited by feasibility of collection. Hair is a novel matrix to measure long-term steroid levels. We developed a liquid chromatography-tandem mass spectrometry (LC/MS) method to assess hair cortisol in individuals at ultra-high risk (UHR) for psychosis as a biomarker of stress.Method: Hair samples from 10 UHR individu...