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ea0014oc6.4 | Cardiovascular endocrinology | ECE2007

Carotid IMT and stiffness, aortic stiffness and pulse pressure: association with hormone therapy in postmenopausal women: baseline findings from the CASHMERE trial

Simon T , Boutouyrie P , Christin-Maitre S , Gompel A , Joanides R , Kearny-Schwartz A , Kuntz Ch , Laurent S , Pannier B , Pornel B , Struijker-Boudier HH , Thuilliez Ch , Van Bortel L , Zannad F , Pithois-Merli I , Jaillon P

Common carotid artery intima media thickness (CCA-IMT), aortic stiffness (carotid-femoral pulse wave velocity-PWV) and central pulse pressure (PP) are early markers of atherosclerosis. The influence of hormonal replacement treatment (HRT) on arterial parameters in menopausal women remains to be investigated.We used baseline data of 665 menopausal women with hypercholesterolemia, screened for the CASHMERE study, a 12-month double-blind randomized trial co...

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ea0014p49 | (1) | ECE2007

Deleterious effects of beta-blockers on arterial stiffness and central pulse pressure in menopausal women: baseline findings from the Cashmere trial

Laurent S , Christin Maitre S , Gompel A , Boutouyrie P , Jaillon P , Thuilliez Ch , Zannad F , Pornel B , Pannier B , Struijker-Boudier H , Van Bortel L , Kuntz Ch , Keanry-Schwartz A , Pithois-Merli I , Simonneau D , Simon T

Beta-blockers (BB) may be less effective than other antihypertensive drugs for stroke prevention in patients with primary hypertension (ASCOT and LIFE studies). Our study compares arterial stiffness and central PP between users (BB+) and non users of BB (BB-), among menopausal women with hypercholesterolemia and no history of CV disease.Methods and Results: We used the baseline data of 664 menopausal women, screened for the Cashmere study, a12-month doub...

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Endocrine Abstracts

Carotid IMT and stiffness, aortic stiffness and pulse pressure: association with hormone therapy in postmenopausal women: baseline findings from the CASHMERE trial

Deleterious effects of beta-blockers on arterial stiffness and central pulse pressure in menopausal women: baseline findings from the Cashmere trial

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