Endocrine Abstracts

Background: Multidisciplinary approach to pituitary disease is highly recommended; it requires a close relationship between expert pituitary surgeons and endocrinologists together with several specialists (e.g. neuroradiologists) in order to provide a high-level standard of care. Although there is evidence that neurosurgeons’ expertise is a key element to achieve better outcomes, also endocrinologists’ role is fundamental but it may sometimes encounter real-life barr...

Background: Adult growth hormone (GH) deficiency (AGHD) is related with alterations in body composition, increased abdominal and visceral adiposity, adverse change in lipid and carbohydrate metabolism, and reduction of bone mineral density (BMD).Aim: To compare baseline outcomes concerning body composition and biochemical/hormonal data among adult patients with AGHD referring to a single endocrinological center and grouped according to their history of r...

Background: Patients with adult growth hormone deficiency (AGHD) have impaired health-related quality of life (QoL). While the effects of reduced muscle mass and vitality-loss on QoL have been well characterized in AGHD, the impact of AGHD on sexual function, a recognized factor influencing well-being, has never been deepened.Aim: To investigate the prevalence of sexual dysfunction in AGHD patients referring to a single endocrinological center and groupe...

Background: AGHD is a recognized clinical entity, but symptoms are quite nonspecific; the lack of objective tools able to measure patients’ health status remains the main barrier in clinical monitoring and treatment.Aim: The MAGHD Study aims improving AGHD patients’ management through a Smartphone app (MAGHDApp) and a fit-watch integrated with a software framework able to merge daily data of patients’ well-being and physical activity with ...

Background: AGHD significantly impacts on metabolism, body composition and quality of life (QoL), including sexuality.AIM: To investigate the impact of a smartphone App on AGHD monitoring, especially QoL and comorbidities as well as on both body composition and biochemical parameters.Methodology: 83 AGHD patients were enrolled in this prospective, open-label, monocentric study (MAGHD Study) of 24-month duration. Patients were evalu...