Endocrine Abstracts

Turner Syndrome (TS) is a genetic disorder which affects 0.5–1 in every 2000 females. It is a multi-systemic disease characterised by a deleted or partially missing X chromosome. This deletion results in a higher incidence of primary ovarian failure and removal of the cardio-protective presence of endogenous oestrogen. The aim of this study was to analyse the prevalence of cardiovascular risk factors in a TS cohort and to assess the steps taken to modify these risk factor...

Introduction and aim: Polycystic Ovary Syndrome (PCOS) is a common disorder associated with a wide range of endocrine and metabolic abnormalities. Obesity is present in about 45–50% of PCOS women. Increased cardiovascular risk factors and evidence of subclinical cardiovascular disease (CVD) have been reported in PCOS. The aim of the present study was to evaluate whether visceral fat amount may be considered as predictor for early CVD in PCOS women.P...

Introduction: The CHEK2 gene is involved in DNA repair. Germline mutations in the CHEK2 gene impair this mechanism, increasing the risk of various cancers, including papillary thyroid cancer (PTC). There are four different mutation variants in the CHEK2 gene in the Polish population: three truncating mutations (1100delC, IVS2+1G>A and del53950) and one missense mutation (I157T).Material: The study included 1,547 PTC patient...