Searchable abstracts of presentations at key conferences in endocrinology

ea0005p161 | Growth and Development | BES2003

Testosterone enhances the effect of growth hormone (GH) to increase IGF-I but exerts an anabolic effect that is independent of GH action

Gibney J , Wolthers T , Males M , Smythe G , Umpleby A , Ho K

Growth hormone (GH) and testosterone are both potent anabolic hormones, but it is not known whether they interact to positively regulate protein metabolism. To address this question, we have carried out two studies, in which we have investigated the impact of GH alone, testosterone alone and combined GH+testosterone, on whole body protein metabolism in hypopituitary men.In the first study, ten subjects received either GH (1.5 units daily) or GH+testosterone (250 milligrams...