Searchable abstracts of presentations at key conferences in endocrinology

ea0081p426 | Pituitary and Neuroendocrinology | ECE2022

3P syndrome: pheochromocytoma, paraganglioma, pituitary adenoma

Havlinova Barbora , Gabalec Filip , Solař Miroslav , Horacek Jiri , Cap Jan

Neuroendocrine tumours, especially pheochromocytomas, paragangliomas and pituitary adenomas, are more common in younger patients in 3rd–5th decade of life. PitNETs are the most common intracranial tumours, while PHEO and PGL are rare. The hormonal activity, signs and symptoms of NET are variable. PGL, PHEO and PitNET in one patient remains an exceptional association. 72 cases of concomitant pituitary adenoma and PGL have been reported to date. The first record of a patien...

ea0016p571 | Obesity | ECE2008

Inflammatory parameters in obesity: lack of influence of weight loss

Sola Eva , Jover Ana , Garcia Katherinne , Salvador Carlos , Morillas Carlos , Hernandez-Mijares Antonio

Introduction: Obesity has been associated with a low-level activation of the acute-phase response. The aim of the present study was to compare inflammatory parameters in patients with obesity and a control group, and to evaluate the effect of weight loss on these parameters.Methods: Sixty-seven severe or morbid obese patients (51 women, 16 men), aged 34±11 years, were compared with 67 normal-weight controls (45 women, 22 men), aged 32±10 years....

ea0016p572 | Obesity | ECE2008

Activated protein C levels in obesity and weight loss influence

Sola Eva , Espana Francisco , Vaya Amparo , Estelles Amparo , Garcia Katherinne , Hernandez-Mijares Antonio

Introduction: Several haemostatic disturbances have been described in obese patients. Nevertheless, the state of coagulation inhibitors has been scarcely studied in these patients. Activated protein C (APC) is the anticoagulant enzyme formed upon activation of the protein C (PC) by the thrombin-thrombomodulin complex on the surface of endothelial cells. Morbid obesity is associated to endothelial dysfunction, which could cause a reduction in APC generation.<p class="abstex...

ea0026p225 | Pituitary | ECE2011

Effect of GH as add-on treatment in severe fibromyalgia syndrome. Results from the IIIb, CT27560 placebo-controlled, multicenter trial

Cuatrecasas Guillem , Alegre Cayetano , Sola Joaquim Fernandez , Gonzalez Maria Jose , Lage Mary , Sesmilo Gemma , Granados Enrique , Domingo Manuel Puig

Introduction: Functional GH deficiency has been described in fibromyalgia (FM). The efficacy of GH as add-on treatment has been suggested in small studies, but little is known in larger and homogeneous populations.Design: Patients (120) were enrolled in a multicenter, randomized, placebo-controlled trial for 18 months (NCT00933686). FM impact questionnaire (FIQ) >75 (severe), duration of FM >18 months, and stability of the standard therapy (amitr...

ea0014p198 | (1) | ECE2007

Evaluation of visceral protein malnutrition in morbid obese patients operated on laparoscopic gastric bypass

Casañ Rosa , Morillas Carlos , Sola Eva , García Katherinne , Yanini Jesus , Jover Ana , Gomez Marcelino , Hernández Antonio

Morbid obesity is associated with a decreased life expectancy and a myriad of serious medical problems. The Roux-en-Y gastric bypass (RYGBP) is the most effective procedure for the treatment of these patients, but it can be responsible of early and late complications. The aim of this prospective study was to evaluate the rate of visceral protein malnutrition (VPM) in morbid obese (MO) patients two years after laparoscopic RYGBP. Albumin (Alb), prealbumin (Prealb), transferrin ...

ea0016p251 | Diabetes and cardiovascular diseases | ECE2008

Frequency of hypertension studied by ambulatory blood pressure monitoring in type two diabetes

Garcia-Malpartida Katherinne , Yanini-Garcia Jesus , Banuls-Morant Celia , Sola-Izquierdo Eva , Morillas-Arino Carlos , Luisa Martinez-Triguero M , Hernandez-Mijares Antonio

Objectives: To know the frequency of hypertension in a group of males with type two diabetes without the antecedent of hypertension, by means of ambulatory blood pressure monitoring (ABPM). To assess the possible differences between the subjects with and without hypertension in age, time of duration of diabetes, obesity and the features of metabolic syndrome.Methods: We included consecutively 55 males with type two diabetes without the antecedent of hype...

ea0081rc13.7 | Rapid Communications 13: Adrenal and Cardiovascular Endocrinology 2 | ECE2022

An observational retrospective study on the association of urine metanephrine levels with cardiometabolic risk in patients with nonfunctioning adrenal incidentaloma

Di Carlo Maria Chiara , Parasiliti Caprino Mirko , Lopez Chiara , Bollati Martina , Bioletto Fabio , Sola Chiara , Ponzetto Federico , Gesmundo Iacopo , Settanni Fabio , Ghigo Ezio , Mengozzi Giulio , Maccario Mauro , GIORDANO Roberta

Background: Several studies argued that the cardiovascular evaluation of patients with nonfunctioning adrenal incidentaloma is of particular importance, even if a direct association seems difficult to underline.Objective: We aimed to evaluate the possibility of stratifying cardiometabolic risk through metanephrine levels in patients with incidentally discovered nonfunctioning adrenal adenoma.Design: In this retrospective cross-sect...