Endocrine Abstracts

Introduction: Hybrid closed loop (HCL) therapy has been shown to improve the glycaemic control in children and adolescents with Type 1 Diabetes. There is however limited data comparing the HCL therapy with conventional insulin pump therapy. We aimed to retrospectively compare the outcomes of hybrid closed loop (Tandem T slim) and conventional insulin pumps.Methodology: Electronic patient records for all the patients using insulin pump therapy at Sheffiel...

Self-monitoring of blood glucose (SMBG) is an important part of diabetes management. Continuous glucose monitoring (CGM) provides real-time measurement of users’ glucose levels. The advantage of CGM is the availability of constant information about glucose levels which helps to predict hyper and hypoglycaemia and to adjust the insulin doses accordingly. NICE guidelines recommend that children and young people with type 1 diabetes and persistent problems with hypoglycaemia...

Background: Paediatric diabetes is predominantly an outpatient based specialty, limiting the training opportunities available to paediatric trainees. At our centre, out of hours diabetes advice calls are managed by paediatric specialty trainees working on the middle grade rota, with 24 hour support from an oncall paediatric diabetes consultant. Feedback locally from families has highlighted the quality of out of hours advice as an area of concern. We aimed to assess the knowle...

Aim: To study the effect of type 1 diabetes mellitus (T1DM) and concurrent autoimmune condition (AI) on long term glycemic control and growth in children.Methods: Twenty-eight children with T1DM and associated autoimmune condition were matched by sex and age at onset with two controls each. HbA1C, height SDS, weight SDS and BMI SDS were measured between 6 months and 5 years after developing T1DM.Results: We included 28 children wit...

Background: GH deficiency has been reported widely in association with myelomeningocele and other pituitary hormone deficiencies occur less frequently. Following an episode of adrenal crisis in a newborn infant with myelomeningocele and multiple pituitary hormone deficiencies we introduced a policy of screening affected, newborn infants for pituitary insufficiency, focusing on thyroid function and cortisol levels.Patients and methods: Data from 26 infant...

The incidence of children presenting with DKA at diagnosis has been on the rise worldwide1. 25.8% of newly diagnosed children had DKA at diagnosis according to the NPDA report (2020/21). 34% of newly diagnosed children in the Yorkshire and Humber(Y&H) region presented in DKA2. Delayed presentation due to lack of awareness is a likely cause for that.Aim: To review the presentations of DKA at diagnosis in the YH r...