Searchable abstracts of presentations at key conferences in endocrinology

ea0035p573 | Endocrine tumours and neoplasia | ECE2014

CD56 immunohistochemical expression: a useful tool for the diagnosis of in thyroid carcinomas of follicular origin

Cornianu Marioara , Golu Ioana , Amzar Daniela , Taban Sorina , Muresan Anca , Dema Alis

Introduction: CD56 (neural cell adhesion molecule/NKH1/LEU19 and LEU7/NHK-1) is an antigen related to follicular epithelium differentiation.Materials and methods: We evaluated the expression of CD56 protein in normal follicular thyroid tissue, 15 non-neoplastic thyroid lesions (nodular hyperplasia–NH, Graves–Basedow disease (GB) and chronic lymphocytic/Hashimoto is thyroiditis (HT) and 38 thyroid neoplasias derived from follicular cells (25 PTC...

ea0026p428 | Thyroid (non cancer) | ECE2011

Proliferative potential of normo- and hyperfunctioning thyroid nodules

Cornianu Marioara , Dema Alis , Golu Ioana , Taban Sorina , Vlad Mihaela , Lazar Elena , Lazureanu Codruta , Grigoras Mirela

Introduction: Thyroid follicular adenomas (FA) and adenomatous nodules (AN) – lesions frequently found in areas with iodine deficiency, can be normo-/hypofunctioning (scintigraphically cold – SCN) or hyperfunctioning (scintigraphically hot – SHN) nodules.Aim: Evaluation of proliferation potential in thyroid nodules on tissue samples obtained at surgery from euthyroid patients clinically diagnosed with SCN and from patients with thyroid hyp...

ea0026p481 | Thyroid cancer | ECE2011

The value of CK19, Ki-67 and p53 expression in the diagnosis of thyroid follicular neoplasms

Cornianu Marioara , Dema Alis , Taban Sorina , Golu Ioana , Muresan Anca , Cornea Remus , Lazar Elena , Faur Alexandra

Introduction: Cytokeratin-19 (CK19), p53 and Ki-67 are some of the proposed markers for differentiating benign from malignant thyroid tumors.Material and method: We evaluated the tissue expression of the three markers in 60 thyroid lesions including: 8 cases of nodular hyperplasia (NH), 16 follicular adenomas (FA), 26 papillary carcinomas (PC) and 10 follicular carcinomas (FC). Tissue sections fixed in formalin and embedded in paraffin were immunohistoch...

ea0022p113 | Bone/Calcium | ECE2010

Diagnostic challenge in child’s bone cystic lesions

Cornianu Marioara , Micle Ioana , Golu Ioana , Vlad Mihaela , Dema Alis , Taban Sorina , Muresan Anca , Lazureanu Codruta

Introduction: Primary hyperparathyroidism (PHP) affects predominantly the adult age (incidence 1/10 000) and it is unusual.The aim of the study: Is to present a rare pathology in a child, which implied interdisciplinary collaboration.Material and method: We present a teenager girl of 16 years old, diagnosed with osteomalacia after a thoracic and pelvis trauma, based on knee and pelvis radiographs (diffuse bone demineralization, tra...

ea0022p447 | Endocrine tumours &amp; neoplasia (<emphasis role="italic">Generously supported by Novartis</emphasis>) | ECE2010

Primary carcinoid as an incidental finding in a mature cystic teratoma of the ovary: case report

Cornianu Marioara , Dema Alis , Golu Ioana , Lazar Elena , Taban Sorina , Faur lexandra , Amzar Daniela , Zosin Ioana

Carcinoid tumors are distinct neuroendocrine neoplasms with characteristic histological, clinical and biological features.Material and methods: An extremely rare case of a primary carcinoid tumor arising in a mature cystic teratoma is reported. A 23-year-old woman was admitted with pain in the lower abdomen and for further examination of a tumor in the left anexa. Transabdominal ultrasonography demonstrated a cystic mass measuring 110/70 mm, with irregul...

ea0016p330 | Endocrine tumours | ECE2008

Ovarian serous and mucinous tumors of low malignant potential: patterns of stromal invasion

Costi Simona , Dema Alis , Golu Ioana , Cornianu Marioara , Taban Sorina , Muresan Anca , Lazar Elena

Purpose: The purpose of this study was to evaluate the histologic spectrum of stromal–epithelial patterns of invasion in ovarian serous and mucinous tumors of low malignant potential.Materials and methods: We retrospectively analyzed 31 cases of borderline ovarian serous and mucinous tumors diagnosed of the Pathology Department of County Hospital Timisoara in a period of 5 years, between 2003 and 2007. Epithelial architecture, the patterns of stroma...

ea0016p756 | Thyroid | ECE2008

The role of elevated microvessel density in the metastatic potential of papillary thyroid carcinoma

Cornianu Marioara , Golu Ioana , Lazar Elena , Dema Alis , Taban Sorina , Costi Simona , Milos Aurora , Zosin Ioana

Introduction: The value of microvessel density (MVD) as a prognostic factor in thyroid carcinomas, and its role in the development of metastasis, remain controversial.Aim: Determination of the relationship between MVD, the histological subtype of PTC, the presence or absence of metastasis in cervical lymph nodes (LN), the recurrence of the disease and AMES prognostic index.Material and method: The study included 32 patients with PT...

ea0020p313 | Clinical case reports and clinical reports | ECE2009

The study of an immunohistochemical aggresivity marker in mammary carcinomas

Maria Muresan Anca , Elena Lazar , Alis Dema , Sorina Taban , Marioara Cornianu , Simona Costi , Ramona Cioroboreanu , Izabella Sargan

Introduction: The mammary cancer is the most frequent malign tumor encountered in females, characterized by a high distant metastasis tendency. Among the potential prognosis factors, we mention the biomarkers that measure or are associated with biologic processes involved in the tumorous progression. The study analyzes the p53 protein’s positivity in correlation with the mammary cancer’s classical prognosis factors: the hystologic type, the histopathologic degree, th...