Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep722 | Obesity | ECE2017

Obesity and fruit and vegetables consumptions in children

Sousa Bruno

Introduction: Obesity is associated with the low consumption of fruit and vegetables.Objective: Evaluate the obesity and the fruit and vegetables consumptions in children after an intervention of school food education program.Methodology: It was implemented a food education program in three classes (n=55) of 1st cycle, on school year (2016/2017) and the evaluation of this action was done comparing fruit and vegetables cons...

ea0056p578 | Obesity | ECE2018

Anthropometric and body composition evolution in individuals in weight loss

Sousa Bruno

Introduction: A large proportion of the Portuguese population has overweight and the process of weight loss is often focused solely on weight. However, it is essential that there is a good evolution of the body composition, namely in the decrease of fat.Objective: Evaluate the anthropometric and body composition evolution in a group of individuals followed for a weight loss.Methodology: This sample consisted of 30 adult and who wer...

ea0090s14.2 | In silico, in vitro, in vivo testing methods for EDC | ECE2023

Screening of metabolism-disrupting chemicals on pancreatic β-Cells

dos Santos Reinaldo Sousa

Diabetes prevalence has been worryingly growing in recent decades, reaching pandemic proportions. Genetic and environmental factors play a role in diabetes aetiology. While the genetic background may predispose individuals to the disease, environmental factors, including exposure to chemical pollutants that can disrupt metabolic functions (also known as metabolism disrupting chemicals or MDCs), may act as triggers to diabetes development. Despite growing evidence suggesting a ...

ea0056s4.3 | Environmental effects on endocrine functions | ECE2018

Environmental contaminants and endocrine disruption: the story of obesogens

Sousa Ana Catarina

According to the World Health Organization, obesity is one of the most important public health challenges of the 21st Century. There is no doubt that excessive calories intake and lack of exercise, are important factors, and that genetics plays a critical role. However, because genes in the population do not change fast enough, other causes must be involved. The involvement of other causes in the etiology of obesity is further strengthened by the fact that obesity is increasin...

ea0035p926 | Pituitary Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2014

Pituitary apoplexy: surgical or conservative management

Sousa Duarte , Marques Olinda , Almeida Rui

Objectives: The rarity of pituitary apoplexy renders it a difficult subject for audit; hence there are no evidence-based standards of optimum care for such patients. The main controversy in management relates to the role of acute surgical intervention. Recently, a more conservative management has been adopted towards patients presenting with this condition. Therefore, it is important to evaluate the differences in outcome between patients submitted to surgical and conservative...

ea0056p726 | Clinical case reports - Pituitary/Adrenal | ECE2018

A family with Kallmann syndrome due to a novel FGFR1 mutation

Martins Ana Sousa , Gregory Louise , Dattani Mehul

Introduction: Kallmann syndrome (KS) is a developmental disorder characterised by hypogonadotropic hypogonadism and anosmia. Known genetic causes account for up to 30% of patients with KS, with FGFR1 mutations being identified in 10%. FGFR1-related KS has an autosomal dominant inheritance with incomplete penetrance. We present a family with KS due to a novel variably penetrant FGFR1 mutation, where the presenting features included cleft lip/palate and anosmia...

ea0090ep1100 | Late Breaking | ECE2023

Diabetes mellitus secondary to BRCA2 gene mutation: the importance of insulin resistance and genetics in dysglycemia

Lopes Valentim , Brito Patricia , Machado Catarina , De Sousa Lages Adriana

Introduction: Diabetes mellitus (DM) results from a defect in insulin secretion and/or its action. The Breast-Cancer Susceptibility Gene 2 (BRCA2), like BRCA1, is a tumour suppressor gene, and its mutation is associated with an increased risk of breast cancer and, in males, testicular cancer. In patients with the BRCA1/2 mutation, the level of Insulin-like Growth Factor (IGF)-1 and, consequently, the peripheral sensitivity to insulin are reduced, suggesting that this ...

ea0049ep660 | Obesity | ECE2017

The surgical approach to obesity in numbers

Raposo Nuno Cordeiro , Ferreira Andreia Sousa , Pratas Sonia , Valadas Cristina

The prevalence of obesity has greatly increased worldwide in the last decades, particularly in Europe and Portugal. It is associated with many health problems, including cardiovascular diseases, cancer and diabetes.Methods: Revision of the clinical records of all 61 patients who underwent bariatric surgery between 2013 and 2015. Analysis of their metabolic profile prior to surgery and its evolution after the operation.Results: 61 p...

ea0049ep1295 | Thyroid (non-cancer) | ECE2017

Treatment of toxic multinodular goiter with 131 radioactive iodine – effects in volume reduction, thyroid function and autoimmunity

Roque Catarina , Sousa Santos Francisco , Pilli Tania , Pacini Furio

Abstract: Radioiodine is a definite treatment option for toxic goiter. We have evaluated volume reduction, function and autoimmunity outcomes with a 15 mCi fixed regimen. Patients with at least one US evaluation before and after Iodine-131 therapy and with at least one year of follow-up were included. TSH, free-T4, antibodies and goiter volume before and yearly after Iodine-131 treatment were analysed for the length of the entire follow-up. The total 151 patients, 72.6% female...

ea0070aep631 | Pituitary and Neuroendocrinology | ECE2020

Functional panhypopituitarism of anorexia

Roque Catarina , Sousa Santos Francisco , Sequeira Duarte João

A 30-year-old male was admitted to the neurotraumatology ward after head trauma with cerebral concussion, subdural & subarachnoidal haemorrhage. The Endocrinologist was called to evaluate high urinary debits. The patient was healthy until 4 years before admission. He enrolled on variate patterns of alimentary restriction that resulted in the loss of 28 kg. Since then he had visited multiple doctors (Cardiology, Haemathology, Psychiatry, Gastroenterology, Urology, Endocrino...