Searchable abstracts of presentations at key conferences in endocrinology

ea0029p398 | Clinical case reports - Pituitary/Adrenal | ICEECE2012

Endocrine hypertension due to primary aldosteronism

Rodrigues P. , Mesquita J. , Souto S. , Belo S. , Morgado P. , Varela A. , Castedo J. , Magalhaes , Carvalho D.

Introduction: Primary aldosteronism (PA) is currently believed to be the most frequent form of secondary endocrine hypertension, accounting for 5–10% of all hypertensive patients. After confirming the diagnosis, adrenal venous sampling (AVS) is considered the most accurate means of distinguishing between unilateral and bilateral adrenal disease.Case report: Female patient, 36 years-old, referred to an Endocrinology appointment in May 2009 due to lef...

ea0029p871 | Endocrine tumours and neoplasia | ICEECE2012

Leydig cell tumor of ovary: a rare case of virilization

Souto S. , Vieira-Baptista P. , Barreto F. , Carvalho-Braga D. , Carvalho D.

Introduction: Leydig cell tumors are a type of steroid cell tumor, account for 0.1% of all ovarian tumors. The clinical presentation is usually a hyperandrogenic state with signs of virilisation. The tumor has a benign behavior, with an excellent prognosis and reversion of symptoms after surgical treatment.Case report: Woman, 81 years-old, nulliparus, with clinic hyperandrogenism and vaginal bleeding during the last year. She had history of dementia synd...

ea0029p1328 | Paediatric endocrinology | ICEECE2012

Short stature due to late-onset congenital adrenal hyperplasia

Rodrigues P. , Souto S. , Costa S. , Moura R. , Alves D. , Freitas P. , Correia C. , Costa C. , Fontoura M.

Introduction: Precocious pubarche is defined as pubic hair onset before age eight in girls and age nine in boys. In 5–20% of cases the cause is late-onset congenital adrenal hyperplasia (LO-CAH), which is due mainly to non-classic 21-hydroxylase deficiency. If not promptly diagnosed, it can lead to accelerated bone maturation, short final height, and in adulthood to severe acne, hirsutism and infertility.Case report: Adolescent male, 15 years-old, h...

ea0026p610 | Clinical case reports | ECE2011

Cholestatic jaundice methimazole-induced or secondary to heart failure?

Souto S B , Rodrigues P , Belo S , Nogueira C , Magalhaes A , Castedo J L , Carvalho-Braga D , Carvalho D

Methimazole-induced cholestatic jaundice is a rare adverse effect, dose-dependent, occurring within the first 3 months of use, usually reversible within 3 months after discontinuing drug therapy.Case report: Woman, 64 years, history of hyperthiroidism since August 2009, under therapy with methimazole 5 mg/day. The patient was referred to endocrinology department in March 2010, with history of heart failure, atrial fibrillation, type 2 diabetes mellitus, ...

ea0026p699 | Diabetes complications | ECE2011

Gilbert syndrome and diabetes: a perfect union?

Matos M J , Souto S B , Oliveira A I , Silva S , Vinha E , Freitas P , Queiros J , Braga D C , Carvalho D

Introduction: Gilbert syndrome is one of the most common inherited diseases, with a prevalence of 5–7%. It is caused by a mutation in UGT1A1 gene, which is in turn responsible for a deficiency in bilirubin glucuronidation. It courses with unconjugated hyperbilirubinemia, and jaundice may occur in adolescence, after fasting, exercise, or in menses, and also with certain drugs. Individuals with Gilbert syndrome seem to have a reduction in the prevalence of micro- and macrov...