Searchable abstracts of presentations at key conferences in endocrinology

ea0026p490 | Thyroid cancer | ECE2011

Retrospective analysis of predictive factors for recurrence during long term follow-up in papillary thyroid cancer patients who had remission after primary treatment

Soyluk Ozlem , Boztepe Harika , Aral Ferihan , Colak Nese

The aim of our study is to detect parameters which may predict recurrences during long-term follow-up in papillary thyroid cancer patients who achieved remission after primary treatment. The data of 492 patients who achieved selected remission criteria after primary treatment were recorded. Remission criteria were for anti-thyroglobulin (antiTg)-negative patients: no uptake in first iodine-131 whole body scan (WBS) after primary treatment and stimulated thyroglobulin (Tg) leve...

ea0041ep163 | Calcium and Vitamin D metabolism | ECE2016

The relationship of Beck depression inventory with vitamin D levels and visceral fat mass in cancer patients

Tuna Savas , Mert Meral , Soyluk Ozlem , Okuturlar Yildiz , Tastekin Didem , Kocoglu Hakan

Introduction: The aim of this study is to determine the relationship of Beck Depression Inventory (BDI) with vitamin D levels and total and visceral fat mass in cancer patients.Methods: A total of 219 patients were included in the study. All patients underwent blood tests including prealbumin, vitamin D. Also patients’ BMI values were calculated and total and visceral fat masses of all patients were measured by bio-impedance analyzer. All subjects c...

ea0041ep939 | Pituitary - Clinical | ECE2016

Clinical features of thyrotropin secreting pituitary adenomas

Uzum Ayse Kubat , Dogru Hulya , Selcukbiricik Ozlem Soyluk , Gul Nurdan , Tanakol Refik , Aral Ferihan

Introduction: Thyrotropin-secreting pituitary adenomas (TSHomas) are a rare cause of hyperthyroidism and represent <1% of all pituitary adenomas. The majority of TSHomas (70%) secrete TSH alone, while mixed adenomas are not infrequent.Design: Herein, we reported the findings of six patients with TSHoma (mean age 44 yr, 4 female, 2 male). Mean TSH value was 15.1 mIU/L (3.3–38.0) who were followed-up in our department.Result...

ea0037ep9 | Adrenal cortex | ECE2015

Salivary cortisol after overnight dexamethasone suppression test in different patient groups

Mert Meral , Tanakol Refik , Karpuzoglu Hande , Abbasoglu Semra Dogru , Soyluk Ozlem , Yarman Sema , Alagol Faruk

Introduction: The aim of this study was to evaluate the worth of the salivary cortisol after overnight 1 mg dexamethasone suppression test (DST) in different patients.Materials and methods: The patient groups of the study consisted of 18 Cushing’s syndrome patients, 12 patients with non-functional adrenal incidentaloma, 37 patients with obesity, 16 patients with hirsutism and 26 healthy control patients. Salivary cortisol (SC) and plasma cortisol af...

ea0037ep207 | Reproduction, endocrine disruptors and signalling | ECE2015

Biochemical and hormonal parameters in patients presenting with hirsutism

Okuturlar Yildiz , Sayilan Samet , Mert Meral , Soyluk Ozlem , Erdogan Ezgi , Harmankaya Ozlem , Kumbasar Abdulbaki

Introduction: It was aimed to evaluate the biochemical and hormonal parameters in female patients with and without polycystic ovary and presenting with symptoms of hirsutism.Materials and methods: In this study, 217 female patients presenting with symptoms of hirsutism were enrolled. Seventy-two female patients having polycystic ovaries by ultrasonography were named as group 1 and 145 female patients with normal ovaries were named as group 2. FSH, LH, pl...

ea0037ep986 | Thyroid (non-cancer) | ECE2015

Propylthiouracil induced anti-neutrophil cytoplasmic antibody-associated vasculitis with skin lesions and granulocytopenia

Tanrikulu Seher , Ince Burak , Selcukbiricik Ozlem Soyluk , Tekin Sakin , Aral Ferihan , Tanakol Refik

Propylthiouracil (PTU) is a widely used drug, and can cause drug-induced vasculitis which is characterized by inflammation and cellular infiltration of small vessels and presence of anti-neutrophil cytoplasmic antibodies (ANCA). We report a case of perinuclear antineutrophil cytoplasmic antibody-associated vasculitis developed during treatment with PTU for Graves’ disease. A 58-year-old woman admitted to the Emergency Department with painful necrotic lesion at her right e...

ea0037ep1341 | Clinical Cases–Thyroid/Other | ECE2015

An aggressive malignant insulinoma: a case report

Oztosun Bugra , Okuturlar Yildiz , Gunaldi Meral , Soyluk Ozlem , Mert Meral , Sayilan Samet , Orman Mehmet , Harmankaya Ozlem

Introduction: Insulinomas are rare pancreatic islet cell tumours with an incidence of four cases per million per year. About 10% of all insulinomas are malignant. We here examined an insulinoma with aggressive driving in a young male patient with severe hypoglycaemia in the emergency room.Case report: 34-year-old male patient was admitted to the emergency department with the blurring of consciousness. Blood glucose was 19 mg/dl, consciousness tends to sl...

ea0035p593 | Endocrine tumours and neoplasia | ECE2014

IGF1 gene polymorphism and thyroid cancer

Soyluk Ozlem , Aral Ferihan , Boztepe Harika , Kapran Yersu , Erbil Yesim , Ustek Duran , Abaci Neslihan , Colak Nese

Aim: Several studies suggested that there is a relationship between serum levels of IGF1 or their polymorhisms and some cancer types. The genetic polymorphism in the region of IGF promoter region which is composed of cytosine–adenine repeats, affects the promoter activity. It is suggested that serum IGF1 levels are inversely associated with the length of CA repeats. There are studies reporting that the carriers of the CA 19 allele are more likely to develop some cancer ty...

ea0035p870 | Pituitary Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2014

Colon cancer metastatic to the pituitary gland: a case report

Soyluk Ozlem , Mert Meral , Tuna Savas , Keskin Ela , Karakaya Pinar , Kaptanogullari Ozlem

Background: Metastases to the pituitary gland are rare events and usually indicate widespread malignant disease. Most common symptoms of pituitary metastases are diabetes insipidus and visual disturbances. The lung and breast are the most common sites of primary tumors that metastasize to the pituitary gland. Pituitary metastasis of gastrointestinal tractus is extremely rare.Case presentation: A 53-year-old woman was given chemotherapy for colon cancer w...

ea0073aep480 | Pituitary and Neuroendocrinology | ECE2021

What should be the optimal testosterone level to improve the symptoms of hypogonadism in male macroprolactinomas?

Caklili Ozge Telci , Ayşe Merve Çelik , Istemihan Zulal , Selcukbiricik Ozlem Soyluk , Yarman Sema

ObjectivesMale prolactinoma patients mostly have hypogonadotropic symptoms. While treatment with dopamine agonists (DAs; such as bromocriptine or cabergoline) leads to recovery of sexual glands, it can lead to impulsive control disorders as an undesirable side effect. The aim of this retrospective study is to determine the level of testosterone that eliminates symptoms, provides fertility and does not cause this undesirable side effect regardless of prol...