Endocrine Abstracts

The aim of our study is to detect parameters which may predict recurrences during long-term follow-up in papillary thyroid cancer patients who achieved remission after primary treatment. The data of 492 patients who achieved selected remission criteria after primary treatment were recorded. Remission criteria were for anti-thyroglobulin (antiTg)-negative patients: no uptake in first iodine-131 whole body scan (WBS) after primary treatment and stimulated thyroglobulin (Tg) leve...

Introduction: The aim of this study is to determine the relationship of Beck Depression Inventory (BDI) with vitamin D levels and total and visceral fat mass in cancer patients.Methods: A total of 219 patients were included in the study. All patients underwent blood tests including prealbumin, vitamin D. Also patients’ BMI values were calculated and total and visceral fat masses of all patients were measured by bio-impedance analyzer. All subjects c...

Introduction: Thyrotropin-secreting pituitary adenomas (TSHomas) are a rare cause of hyperthyroidism and represent <1% of all pituitary adenomas. The majority of TSHomas (70%) secrete TSH alone, while mixed adenomas are not infrequent.Design: Herein, we reported the findings of six patients with TSHoma (mean age 44 yr, 4 female, 2 male). Mean TSH value was 15.1 mIU/L (3.3–38.0) who were followed-up in our department.Result...

Introduction: The aim of this study was to evaluate the worth of the salivary cortisol after overnight 1 mg dexamethasone suppression test (DST) in different patients.Materials and methods: The patient groups of the study consisted of 18 Cushing’s syndrome patients, 12 patients with non-functional adrenal incidentaloma, 37 patients with obesity, 16 patients with hirsutism and 26 healthy control patients. Salivary cortisol (SC) and plasma cortisol af...

Introduction: It was aimed to evaluate the biochemical and hormonal parameters in female patients with and without polycystic ovary and presenting with symptoms of hirsutism.Materials and methods: In this study, 217 female patients presenting with symptoms of hirsutism were enrolled. Seventy-two female patients having polycystic ovaries by ultrasonography were named as group 1 and 145 female patients with normal ovaries were named as group 2. FSH, LH, pl...

Propylthiouracil (PTU) is a widely used drug, and can cause drug-induced vasculitis which is characterized by inflammation and cellular infiltration of small vessels and presence of anti-neutrophil cytoplasmic antibodies (ANCA). We report a case of perinuclear antineutrophil cytoplasmic antibody-associated vasculitis developed during treatment with PTU for Graves’ disease. A 58-year-old woman admitted to the Emergency Department with painful necrotic lesion at her right e...

Introduction: Insulinomas are rare pancreatic islet cell tumours with an incidence of four cases per million per year. About 10% of all insulinomas are malignant. We here examined an insulinoma with aggressive driving in a young male patient with severe hypoglycaemia in the emergency room.Case report: 34-year-old male patient was admitted to the emergency department with the blurring of consciousness. Blood glucose was 19 mg/dl, consciousness tends to sl...

Aim: Several studies suggested that there is a relationship between serum levels of IGF1 or their polymorhisms and some cancer types. The genetic polymorphism in the region of IGF promoter region which is composed of cytosine–adenine repeats, affects the promoter activity. It is suggested that serum IGF1 levels are inversely associated with the length of CA repeats. There are studies reporting that the carriers of the CA 19 allele are more likely to develop some cancer ty...

Background: Metastases to the pituitary gland are rare events and usually indicate widespread malignant disease. Most common symptoms of pituitary metastases are diabetes insipidus and visual disturbances. The lung and breast are the most common sites of primary tumors that metastasize to the pituitary gland. Pituitary metastasis of gastrointestinal tractus is extremely rare.Case presentation: A 53-year-old woman was given chemotherapy for colon cancer w...

ObjectivesMale prolactinoma patients mostly have hypogonadotropic symptoms. While treatment with dopamine agonists (DAs; such as bromocriptine or cabergoline) leads to recovery of sexual glands, it can lead to impulsive control disorders as an undesirable side effect. The aim of this retrospective study is to determine the level of testosterone that eliminates symptoms, provides fertility and does not cause this undesirable side effect regardless of prol...