Endocrine Abstracts

Growth hormone deficiency (GHD) in adulthood has been associated with increased central adiposity, reduced lean body mass, increased cardiovascular risk, reduced bone mineral density with increased fracture risk and decreased quality of life. GH replacement might improve these alterations.We evaluated the long-term metabolic effects of GH replacement on bone metabolism and body composition of 24 GHD patients (20 males, mean age 38±11 years, 20 adult...