Endocrine Abstracts

Introduction: Duchenne Muscular Dystrophy (DMD) is an X-linked recessive neuromuscular disorder causing progressive muscular degeneration and weakness. The survival of patients with DMD has improved with multi-disciplinary team input. Sub-specialties have moved towards anticipatory diagnostic and therapeutic strategies which focus on prevention and treatment of modifiable disease complications. Endocrine complications of DMD include impaired growth, delayed pu...

Background: A recent case of a seven-year-old boy developing diabetes insipidus, central hypothyroidism and growth hormone deficiency following a severe traumatic brain injury (TBI) highlighted a lack of surveillance for post-TBI pituitary dysfunction within the tertiary paediatric hospital of Northern Ireland. There are limited paediatric studies into this area, but evidence suggests post-TBI hypopituitarism occurs fairly frequently in children; with prevalence of isolated ho...