Searchable abstracts of presentations at key conferences in endocrinology

ea0022oc5.3 | Reproduction & Thyroid | ECE2010

Socio-economic factors and mortality in Turner syndrome: a registry study

Stochholm Kirstine , Gravholt Claus

In Turner persons questionnaire surveys have identified quality of life, perception of health and education to be at a similar or higher level compared to the background population. To shed further light on these seemingly paradoxical findings in Turner persons we aimed to analyze various socio-economic parameters in Turner persons compared to an age-matched female background population.All diagnosed Turner syndrome women nationwide (n=977) were i...

ea0032p339 | Developmental Endocrinology | ECE2013

The prevalence, incidence and diagnostic delay in 46,XY females; a Danish national cohort study

Berglund Agnethe , Stochholm Kirstine , Fedder Jens , Hojbjerg Gravholt Claus

Introduction: Disorders of sex development where females have a 46,XY karyotype can be seen. Main reasons for this are the conditions of androgen insensitivity syndrome (AIS) and gonadal dysgenesis. The clinical phenotype of both conditions is variable and can present from an undervirilized or infertile male to an individual with ambiguous genitalia at birth, to a pure female phenotype with unambiguous genitalia, who first present in adolescence with primary amenorrhoea and/or...

ea0063oc14.5 | Sex Hormones | ECE2019

The pattern of cancer occurrence in Turner syndrome

Viuff Mette , Berglund Agnethe , Juul Svend , Stochholm Kirstine , Gravholt Claus H

Background: Studies have shown that the overall risk of cancer is not increased in Turner syndrome (TS). However, the pattern of cancer occurrence may be different than in the background population.Aim: To describe the cancer morbidity pattern in TS.Design: Nationwide epidemiological study using Danish registries on morbidity.Methods: 1,156 Females with TS diagnosed during 1960–2014 were identified using...

ea0049oc1.4 | Adrenal-Basic & Clinical | ECE2017

The epidemiology of pheochromocytoma: increasing incidence and changing clinical presentation. A population-based retrospective study 1977–2015

Ebbehoj Andreas Ladefoged , Sondergaard Esben , Trolle Christian , Stochholm Kirstine , Poulsen Per Logstrup

Pheochromocytoma is a rare disease but frequently poses a diagnostic dilemma due to the unspecific symptoms and its potentially life-threatening nature. There is a perception of an increase in the incidence of pheocromocytomas in recent years, but no data on time trends exist. We obtained data from The Danish National Registry of Patients, The Danish Registry of Causes of Death, and The National Pathology Registry for all persons registered with pheochromocytoma in 1977–2...

ea0022p482 | Female reproduction | ECE2010

Ascending aortic dilatation in Turner syndrome: the natural history

Mortensen Kristian , Hjerrild Britta , Stochholm Kirstine , Andersen Niels , Soerensen Keld , Lundorf Erik , Christiansen Jens , Gravholt Claus

Background: Aortic dissection causes excess mortality in Turner syndrome, and this increased risk is associated with aortic dilation, congenital cardiovascular abnormalities, karyotype, and blood pressure. But risk factor identification is inadequate, and the natural course of aortopathy in Turner syndrome is poorly investigated.Design and methods: Prospective follow-up study in women with Turner syndrome (n=102, examined twice) and healthy age-ma...

ea0070aep777 | Pituitary and Neuroendocrinology | ECE2020

Acromegaly is associated with reduced socioeconomic status and more so in female patients: A nationwide population-based study

Dal Jakob , Nielsen Eigil H , Feldt-Rasmussen Ulla , Andersen Marianne , Feltoft Claus , Vestergaard Peter , Stochholm Kirstine , Otto Jorgensen Jens

Context: Acromegaly is a rare and insidious disease associated with severe somatic morbidity but data on socioeconomic status are scarce.Objective: To study the socioeconomic status in acromegaly in a population based, nationwide follow-up study.Patients and Methods: All incident cases of acromegaly (n = 576) during the period 1997–2010 were included, representing 10.116 years at risk. For every patient, 100 pers...

ea0032p849 | Pituitary – Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2013

The prevalence of insufficient test responses in patients with traumatic brain injury compared to healthy controls – results from The Danish National Study on posttraumatic hypopituitarism

Klose Marianne , Laurberg Peter , Frederiksen Louise , Stochholm Kirstine , Janukonyte Jurgita , Christiansen Jens Sandahl , Andersen Marianne , Feldt-Rasmussen Ulla

Introduction: We questioned the justification of general recommendations for assessment of hypopituitarism in patients with traumatic brain injury (TBI), and aimed to describe the prevalence of hypopituitarism in a national TBI population of patients admitted to a Danish hospital in 2008, as compared to healthy controls.Patients and methods: We included 463 patients (18–65 years) hospitalized ≥24 h, with more than subtle TBI as indicated by lo...

ea0056gp44 | Adrenal medulla and NETs | ECE2018

Mortality in patients with Pheochromocytoma: a population-based study 1977–2016

Ebbehoj Andreas Ladefoged , Sondergaard Esben , Jacobsen Sarah Forslund , Trolle Christian , Robaczyk Maciej Grzegorz , Rasmussen AEse Krogh , Feldt-Rasmussen Ulla , Thomsen Reimar Wernich , Stochholm Kirstine , Poulsen Per Logstrup

Background: Pheochromocytomas and catecholamine-secreting paragangliomas (PPGL) are rare catecholamine-producing tumors. Due to the rarity, limited data on prognosis exists and data are mainly from tertiary centers with potential referral bias. Here, we present population-based mortality data over an observation period of 40 years.Materials and methods: We identified a cohort of 198 PPGL patients diagnosed 1 January 1977 to 31 December 2016 in North and ...

ea0090p437 | Pituitary and Neuroendocrinology | ECE2023

Acromegaly management in the Scandinavian countries – a DELPHI consensus survey

Arlien-Soborg Mai C. , Dal Jakob , Heck Ansgar , Stochholm Kirstine , H Nielsen Eigil , Feltoft Claus , Krogh Rasmussen AEse , Feldt-Rasmussen Ulla , Andreassen Mikkel , Klose Marianne , Leo Nielsen Torben , Andersen Marianne , Lehmann Christensen Louise , Krogh Jesper , Jarlov Anne , Lyngvi Fougner Stine , Nermoen Ingrid , Bollerslev Jens , Oksnes Marianne , Dahlqvist Per , Olsson Tommy , Berinder Katarina , Hoybye Charlotte , Petersson Maria , AEkerman Anna-Karin , Wahlberg Jeanette , Ekman Bertil , Eden Engstrom Britt , Johannsson Gudmundur , Ragnarsson Oskar , Agusta Sigurjonsdottir Helga , Burman Pia , Otto Jorgensen Jens

Background: Acromegaly is associated with increased morbidity and mortality if left untreated. The therapeutic options include surgery, medical treatment, and radiotherapy. Guidelines regarding treatment algorithms and follow-up vary considerably.Aim: To evaluate consensus on the treatment and follow-up of acromegaly in the Scandinavian countries.Methods: To map the landscape of acromegaly management in the Scandinavian countries, ...