Endocrine Abstracts

Objectives: Finding novel tumor markers capable to recognize aggressive papillary thyroid carcinoma (PTC) forms are of great importance. We evaluated hsa-microRNA-204-3p (miR-204-3p) for differential diagnosis of thyroid tumors and assessed its prognostic usefulness.Methods: MiR-204-3p levels were determined in 77 PTC cases of diverse histological variants, 12 cases of follicular thyroid adenoma (FTA), and 89 matched nonmalignant thyroid epithelial tissu...

Background: Solitary fibrous tumor of pleura represents a prototypical mesenchymal neoplasm that induces non-islet cell tumor hypoglycemia due to overproduction of insulin-like growth factor 2, named Dodge Potter syndrome.Case Presentation: An 86-year-old man, non-diabetic, was admitted to hospital with a few months history of repetitive hypoglycemic symptoms and documented low blood glucose of 1.9 and 1.2 mmol/L on two occasions when he lost consciousne...

Background: The partial or complete hypopituitarism is described as late complication of hemorrhagic fever with renal syndrome (HFRS). Imaging methods of pituitary gland examination in the chronic phase showed pituitary atrophy, but a precise pathogenic mechanism that causes pituitary damage in HRFS remains unclear. While hypopituitarism in HFRS is rarely described, cardiac failure as a known complication of hypopituitarism is even more rarely described. We present a case of s...

Objectives: ETS-1 (E26 transformation-specific) is a transcription factor associated with the progression of carcinomas of various origins. Its expression in PTC is poorly described, and the findings are controversial. This study aimed to describe ETS-1 protein expression in papillary thyroid carcinoma (PTC) and to evaluate the potential influence of miR-204-3p on the ETS-1 protein expression in PTC since the bioinformatic analysis revealed that miR-204-3p shares a seed sequen...