ea0011p537 | Endocrine tumours and neoplasia | ECE2006
Unger N
, Serdiuk I
, Saeger W
, Wiedemeyer H
, Van de Nes J
, Schulz S
, Stolke D
, Mann K
, Petersenn S
For somatostatin, five receptor subtypes (sst1-5) have been identified that are widely distributed in various endocrine tissues and tumors. Potent somatostatin analogs like octreotide, lanreotide and the new multiligand SOM230 with different binding properties to the receptor subtypes - have been developed. We examined somatostatin receptor protein expression in 134 pituitary tumors of various etiologies. Immunostaining was performed with specific polyclonal anti...