Searchable abstracts of presentations at key conferences in endocrinology

ea0073aep663 | Thyroid | ECE2021

Thyroid-receptor antibodies, immunoglubulin E and antinuclear antibodies in patients with Graves’ disease and their association with Graves’ orbitopathy and smoking habits

Stoynova Mariya , Shinkov Alexander , Kirilov Georgi , Kovatcheva Roussanka

IntroductionThyrotropin-receptor antibodies (TRAb) play a key role in the pathogenesis of Graves’ disease (GD) and Graves’ orbitopathy (GO) and are important for the diagnosis of both diseases. Elevated levels of immunoglobulin E (IgE) and antinuclear antibodies (ANA) were also found in GD patients. Smoking is a risk factor for GD and GO development and GO progression. We aimed to assess the associations between TRAb, IgE and ANA, and the prese...