Searchable abstracts of presentations at key conferences in endocrinology

ea0077p70 | Metabolism, Obesity and Diabetes | SFEBES2021

Real-world metabolic outcomes of semaglutide use in patients with type 2 diabetes: a retrospective study from a single centre in the United Arab Emirates

Allum Matthew , Buckley Adam , Lessan Nader , Mohammed Nagi , Suliman Mohamed , Suliman Sara , Elsheikh Mohgah

Background: The Glucagon-like peptide-1 receptor agonist (GLP1RA) semaglutide has shown improvements in glycaemia and other metabolic parameters for patients with type 2 diabetes (T2D) in clinical trials. Published real-world data are sparse and there are none from the Middle East where semaglutide became available in 2020.Method and Results: We retrospectively gathered data for 289 patients (median age 50 years (IQR 42-57), 36% female, 87% Emirati and 8...

ea0070ep143 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

Lipoatrophy in a patient with type 1 diabetes: Genetic or immunological?

Ashraf Tanveer , Awad Nisreen , Suliman Sara , Helal Radwa , Naqvi Safdar , Lessan Nader

We report the case of a 28-year-old Emirati lady with type 1 diabetes (weight 51 kg, BMI 20.82 kg/m2) diagnosed at 3 years of age who presented to our centre with problems at her insulin injection sites. She had poor glycaemic control and her diabetes was complicated by retinopathy; other past medical history included vitamin D deficiency. All her seven siblings had diabetes and were on insulin; both parents had type 2 diabetes.In 2017, she wa...

ea0073aep164 | Diabetes, Obesity, Metabolism and Nutrition | ECE2021

The short-term effect of surgical and pharmacological intervention in obesity caused by MC4R deficiency: A single centre experience

Radha Saradalekshmi Koramannil , Fojas Esphie Grace , Ali Tomader , Suliman Sara GI , Lessan Nader

IntroductionMelanocortin-4-receptor (MC4R) deficiency is the commonest of the rare monogenic forms of obesity. Bariatric surgery (BS) is the most efficacious treatment modality in the more ’common’ polygenic obesity. Effect of surgical and drug treatment in obesity due to MC4R deficiency is not well-established.AimWe aimed to explore the effects of BS and drug treatment among the confirmed cases of ...