Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep1285 | Thyroid (non-cancer) | ECE2017

Improved diagnostics with increased treatment of hypothyroidism during pregnancy – a 10 year study of Finnish pregnant women

Turunen Suvi , Mannisto Tuija , Hartikainen Anna-Liisa , Gissler Mika , Lahesmaa-Korpinen Anna-Maria , Vaarasmaki Marja , Suvanto Eila

Thyroid diseases affect up to 4% of all pregnancies. Several evidence-based recommendations have been created to observe and treat thyroid diseases in pregnant women. We studied whether the diagnostics and treatment of hypothyroidism among pregnant women have improved in the course of time. Data consisted of all singleton pregnancies (N=571785) during 2004–2013 in Finland, collected from the Finnish Medical Birth Register (MBR). Data on maternal thyroid diseases ...

ea0026oc1.2 | Thyroid/Adrenal | ECE2011

ESE Young Investigator Award

Mannisto T , Ruokonen A , Surcel H-M , Bloigu A , Vaarasmaki M , Pouta A , Jarvelin M-R , Hartikainen A-L , Suvanto Eila

Introduction: Pregnancy is a stress test on maternal thyroid and pregnant women may be more susceptible to thyroid dysfunction. Consequences of this may be harmful for the mother and fetus. Smoking has been associated with alterations in thyroid hormone concentrations, but little knowledge exists on this association in pregnant women.Subjects and methods: The study population is large, prospective population-based Northern Finland Birth Cohort 1986 (n...

ea0099rc1.6 | Rapid Communications 1: Reproductive and Developmental Endocrinology | ECE2024

The prevalence of serious autoimmune diseases is increased in women with premature ovarian insufficiency in Finland – A population-based study

Savukoski Susanna , Silven Heidi , Pesonen Paula , Pukkala Eero , Gissler Mika , Suvanto Eila , Ollila Meri-Maija , Niinimaki Maarit

Introduction: Autoimmunity is an important etiological factor of premature ovarian insufficiency (POI, menopause <40 years). It has been estimated that 4-50 % of POI cases are of autoimmune origin. Only a few studies, with sample sizes of dozens to hundreds POI cases, have investigated the prevalence of autoimmune diseases in women with POI. We aimed to assess in an essentially larger data set the prevalence of severe autoimmune diseases treated in tertiary care prior to P...

ea0026oc1.3 | Thyroid/Adrenal | ECE2011

Maternal thyroid dysfunction during pregnancy and thyroid function of the offspring at the age of 16 years

Pakkila Fanni , Mannisto Tuija , Bloigu Aini , Vaarasmaki Marja , Hartikainen Anna-Liisa , Ruokonen Aimo , Pouta Anneli , Jarvelin Marjo-Riitta , Surcel Helja-Marja , Suvanto Eila

Introduction: Foetus is dependent on maternal thyroid hormone production during the first trimester. Thus, maternal thyroid dysfunction and thyroid antibodies may affect thyroid function of the offspring.Subjects and methods: We studied a subcohort (n=2000 mother–child-pairs) from a prospective population-based Northern Finland Birth Cohort 1986 (singleton births, total n=9247) covering data throughout pregnancy, childhood and adolesce...